PMID- 24163487
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211021
IS  - 0142-2421 (Print)
IS  - 0142-2421 (Linking)
VI  - 45
IP  - 1
DP  - 2013 Jan
TI  - Characterization of individual nano-objects with nanoprojectile-SIMS.
PG  - 329-332
LID - 10.1002/sia.5084
AB  - Secondary ion mass spectrometry (SIMS) applied in the event-by-event 
      bombardment/detection mode is uniquely suited for the characterization of 
      individual nano-objects. In this approach, nano-objects are examined one-by-one, 
      allowing for the detection of variations in composition. The validity of the 
      analysis depends upon the ability to physically isolate the nano-objects on a 
      chemically inert support. This requirement can be realized by deposition of the 
      nano-objects on a Nano-Assisted Laser Desorption/Ionization (NALDI) plate. The 
      featured nanostructured surface provides a support where nano-objects can be 
      isolated if the deposition is performed at a proper concentration. We demonstrate 
      the characterization of individual nano-objects on a NALDI plate for two 
      different types of nanometric bacteriophages: Qbeta and M13. Scanning electron 
      microscope (SEM) images verified that the integrity of the phages is preserved on 
      the NALDI substrate. Mass spectrometric data show secondary ions from the phages 
      are identified and resolved from those from the underlying substrate.
FAU - Liang, C-K
AU  - Liang CK
AD  - Department of Chemistry, Texas A&M University, College Station, TX, 77843-3255, 
      USA.
FAU - Verkhoturov, S V
AU  - Verkhoturov SV
FAU - Bisrat, Y
AU  - Bisrat Y
FAU - Dikler, S
AU  - Dikler S
FAU - Debord, J D
AU  - Debord JD
FAU - Fernandez-Lima, F A
AU  - Fernandez-Lima FA
FAU - Schweikert, E A
AU  - Schweikert EA
FAU - Della-Negra, S
AU  - Della-Negra S
LA  - eng
GR  - R00 GM106414/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PL  - England
TA  - Surf Interface Anal
JT  - Surface and interface analysis : SIA
JID - 101479368
PMC - PMC3806210
MID - NIHMS518665
OTO - NOTNLM
OT  - NALDI
OT  - ToF-SIMS
OT  - event-by-event SIMS analysis
OT  - gold clusters
OT  - nano-objects
EDAT- 2013/10/29 06:00
MHDA- 2013/10/29 06:01
PMCR- 2013/10/23
CRDT- 2013/10/29 06:00
PHST- 2013/10/29 06:00 [entrez]
PHST- 2013/10/29 06:00 [pubmed]
PHST- 2013/10/29 06:01 [medline]
PHST- 2013/10/23 00:00 [pmc-release]
AID - 10.1002/sia.5084 [doi]
PST - ppublish
SO  - Surf Interface Anal. 2013 Jan;45(1):329-332. doi: 10.1002/sia.5084.