PMID- 24164042
OWN - NLM
STAT- MEDLINE
DCOM- 20150708
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 31
IP  - 7
DP  - 2013 Jul
TI  - [Determination of zearalanol and related mycotoxins in pork by solid-phase 
      extraction coupled with ultra performance liquid chromatography-tandem mass 
      spectrometry].
PG  - 703-8
AB  - A method was established for the determination of six compounds of zearalanol and 
      related mycotoxins in pork and its products. After hydrolysis of the target 
      compounds in the pork by beta-glucosidase/sulfatase, they were extracted with 
      methanol aqueous solution and further purified by an HLB column. The separation 
      was performed on a BEH C18 column with gradient elution using acetonitrile-water 
      as mobile phases. The analytes were determined by mass spectrometry using 
      electrospray ionization (ESI) in negative scan mode and multiple reaction 
      monitoring (MRM) mode. alpha-Zearalenol-D7 and beta-zearalenol-D7 were used as 
      internal standards. The good linearities (r > 0. 999) were achieved for the six 
      compounds over the range of 1. 0 - 100 microg/L based on the internal standard 
      calibration. The detection limits of the method were 0.03 -0.09 microg/kg. The 
      mean recoveries of the six target compounds spiked at three levels from 1. 0 - 
      10. 0 microg/kg ranged from 76. 7% to 100. 5% with the relative standard 
      deviations (RSDs) less than 20%. The proposed method is simple, sensitive, 
      reproducible, and complies with the regulations for the determination of trace 
      contaminant residues in food matrice.
FAU - Li, Liping
AU  - Li L
AD  - Institute of Nutrition and Food Hygiene, Beijing Center for Disease Control 
      &Prevention, Beijing 100013, China.
FAU - Fan, Sai
AU  - Fan S
FAU - Zhao, Rong
AU  - Zhao R
FAU - Li, Bing
AU  - Li B
FAU - Liu, Wei
AU  - Liu W
FAU - Wu, Guohua
AU  - Wu G
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Mycotoxins)
RN  - 0 (zearalenol)
RN  - 76LO2L2V39 (Zeranol)
SB  - IM
MH  - Animals
MH  - Chromatography, High Pressure Liquid
MH  - Food Contamination/*analysis
MH  - Meat/*analysis
MH  - Mycotoxins/*analysis
MH  - Solid Phase Extraction
MH  - Spectrometry, Mass, Electrospray Ionization
MH  - Swine
MH  - Tandem Mass Spectrometry
MH  - Zeranol/*analogs & derivatives/analysis
EDAT- 2013/10/30 06:00
MHDA- 2015/07/15 06:00
CRDT- 2013/10/30 06:00
PHST- 2013/10/30 06:00 [entrez]
PHST- 2013/10/30 06:00 [pubmed]
PHST- 2015/07/15 06:00 [medline]
AID - 10.3724/sp.j.1123.2012.12033 [doi]
PST - ppublish
SO  - Se Pu. 2013 Jul;31(7):703-8. doi: 10.3724/sp.j.1123.2012.12033.