PMID- 24166188
OWN - NLM
STAT- MEDLINE
DCOM- 20140703
LR  - 20220317
IS  - 1098-9056 (Electronic)
IS  - 0734-0478 (Linking)
VI  - 34
IP  - 3
DP  - 2013 Aug
TI  - Amount of therapy matters in very early aphasia rehabilitation after stroke: a 
      clinical prognostic model.
PG  - 129-41
LID - 10.1055/s-0033-1358369 [doi]
AB  - BACKGROUND AND AIM: The effects of very early aphasia therapy on recovery are 
      equivocal. This article examines predictors of very early aphasia recovery 
      through statistical modeling. METHODS: This study involved a secondary analysis 
      of merged data from two randomized, single-blind trials conducted in Australian 
      acute and subacute hospitals. Study 1 (n = 59) compared daily therapy to usual 
      ward care for up to 4 weeks poststroke in patients with moderate to severe 
      aphasia. Study 2 (n = 20) compared daily group therapy to daily individual 
      therapy for 20 1-hour sessions over 5 weeks, in patients with mild to severe 
      aphasia. The primary outcome measure was the Western Aphasia Battery Aphasia 
      Quotient (AQ) at therapy completion. This analysis used regression modeling to 
      examine the effects of age, baseline AQ and baseline modified Rankin Scale (mRS), 
      average therapy amount, therapy intensity, and number of therapy sessions on 
      aphasia recovery. RESULTS: Baseline AQ (p = 0.047), average therapy amount (p = 
      0.030), and baseline mRS (p = 0.043) were significant predictors in the final 
      regression model, which explained 30% (p < 0.001) of variance in aphasia 
      recovery. CONCLUSION: The amount of very early aphasia therapy could 
      significantly affect communication outcomes at 4 to 5 weeks poststroke. Further 
      studies should include amount of therapy provided to enhance reliability of 
      prognostic modeling in aphasia recovery.
CI  - Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
FAU - Godecke, Erin
AU  - Godecke E
AD  - Faculty of Health, Engineering and Science, Edith Cowan University, Joondalup, 
      Western Australia, Australia.
FAU - Rai, Tapan
AU  - Rai T
FAU - Ciccone, Natalie
AU  - Ciccone N
FAU - Armstrong, Elizabeth
AU  - Armstrong E
FAU - Granger, Andrew
AU  - Granger A
FAU - Hankey, Graeme J
AU  - Hankey GJ
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
DEP - 20131028
PL  - United States
TA  - Semin Speech Lang
JT  - Seminars in speech and language
JID - 8405117
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Aphasia/etiology/*rehabilitation/*therapy
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Models, Statistical
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Randomized Controlled Trials as Topic
MH  - Regression Analysis
MH  - Secondary Prevention
MH  - *Speech Therapy
MH  - Stroke/complications/therapy
MH  - Stroke Rehabilitation
MH  - Time Factors
EDAT- 2013/10/30 06:00
MHDA- 2014/07/06 06:00
CRDT- 2013/10/30 06:00
PHST- 2013/10/30 06:00 [entrez]
PHST- 2013/10/30 06:00 [pubmed]
PHST- 2014/07/06 06:00 [medline]
AID - 10.1055/s-0033-1358369 [doi]
PST - ppublish
SO  - Semin Speech Lang. 2013 Aug;34(3):129-41. doi: 10.1055/s-0033-1358369. Epub 2013 
      Oct 28.