PMID- 24169329 OWN - NLM STAT- MEDLINE DCOM- 20150514 LR - 20131030 IS - 0376-2491 (Print) IS - 0376-2491 (Linking) VI - 93 IP - 28 DP - 2013 Jul 23 TI - [Serum parathyroid hormone levels predict hospitalization in outpatients of heart failure: a preliminary study]. PG - 2205-8 AB - OBJECTIVE: To evaluate the predicative value of serum parathyroid hormone (PTH) levels in outpatients of heart failure (HF) for hospitalization. METHODS: A total of 102 consecutive HF outpatients were enrolled. The receiver operating characteristic (ROC) curves demonstrated the optimal cut-off points of PTH levels for hospitalization due to HF. And Logistic regression analysis model was employed to analyze the independent association between PTH and hospitalization for HF. RESULTS: The more advanced grade of New York Heart Association (NYHA), the higher serum level of PTH. The ROC curves showed PTH levels >/= 56.05 ng/L were the optimal cut-off point for hospitalization for HF with a sensitivity of 90.0%, a specificity of 89.2% and the area under ROC curve of 0.92. After adjustment for predictors for hospitalization due to HF (gender, age, diabetes mellitus, hypertension, left ventricular ejection fraction, estimated glomerular filtration rate and brain natriuretic peptide), PTH levels were associated with hospitalization due to HF (OR = 1.282, 95%CI 1.026-1.362). CONCLUSION: The serum level of PTH in HF outpatients is an independent predicator for hospitalization due to HF. FAU - Wu, Gang-yong AU - Wu GY AD - Department of Cardiology, No.101 Hospital of PLA, Wuxi 214044, China. FAU - Zong, Gang-jun AU - Zong GJ FAU - Chen, Jing-kai AU - Chen JK FAU - Chen, Man-qing AU - Chen MQ FAU - Xia, Yang AU - Xia Y FAU - Wang, Xiao AU - Wang X FAU - Wang, Lu-lu AU - Wang LL FAU - Shi, Yi-cheng AU - Shi YC FAU - Wang, Tian-xiao AU - Wang TX FAU - Wang, Xiao-ying AU - Wang XY FAU - Jin, Wei-dong AU - Jin WD LA - chi PT - English Abstract PT - Journal Article PL - China TA - Zhonghua Yi Xue Za Zhi JT - Zhonghua yi xue za zhi JID - 7511141 RN - 0 (Parathyroid Hormone) SB - IM MH - Heart Failure/*diagnosis MH - Hospitalization MH - Humans MH - Outpatients MH - Parathyroid Hormone/*blood MH - ROC Curve MH - Sensitivity and Specificity MH - Ventricular Function, Left EDAT- 2013/10/31 06:00 MHDA- 2015/05/15 06:00 CRDT- 2013/10/31 06:00 PHST- 2013/10/31 06:00 [entrez] PHST- 2013/10/31 06:00 [pubmed] PHST- 2015/05/15 06:00 [medline] PST - ppublish SO - Zhonghua Yi Xue Za Zhi. 2013 Jul 23;93(28):2205-8.