PMID- 24170653
OWN - NLM
STAT- MEDLINE
DCOM- 20150408
LR  - 20131030
IS  - 2327-6924 (Electronic)
IS  - 2327-6886 (Linking)
VI  - 25
IP  - 9
DP  - 2013 Sep
TI  - Therapeutic options for lowering LDL-C in type 2 diabetes: a nurse practitioner's 
      perspective.
PG  - 488-94
LID - 10.1002/2327-6924.12053 [doi]
AB  - PURPOSE: The majority of patients with type 2 diabetes mellitus (T2DM) have 
      multiple risk factors for cardiovascular disease (CVD). Low-density lipoprotein 
      cholesterol (LDL-C) is a key therapeutic target to reduce CVD risk. This article 
      reviews therapeutic strategies that nurse practitioners (NPs) may use in the 
      management of patients with T2DM requiring lipid management. DATA SOURCES: The 
      evidence used in developing this review included evidence-based reviews, clinical 
      trials, guidelines, and consensus statements. Relevant publications were 
      identified through a search of the literature using PubMed and other search 
      engines. CONCLUSIONS: Lowering LDL-C levels may reduce CVD risk, but achieving 
      goals can be challenging. Lifestyle modifications (including diet, exercise, and 
      smoking cessation) are key components of lipid management and reduction of CVD 
      risk. Statins can be effective to reduce lipids. However, patients may not 
      achieve lipid goals with monotherapy or may experience intolerable adverse 
      effects. Alternative statins or statins along with other lipid-lowering agents 
      remain good options. IMPLICATIONS FOR PRACTICE: Achieving LDL-C goals requires a 
      comprehensive treatment plan that incorporates lifestyle and pharmacologic 
      interventions. Patient commitment in setting goals and self-management is 
      essential. NPs can play an important role in educating patients as well as 
      prescribing appropriate treatments.
CI  - (c)2013 The Author(s) (c)2013 American Association of Nurse Practitioners.
FAU - Lew, Kelley Newlin
AU  - Lew KN
AD  - School of Nursing, University of Connecticut, Storrs, Connecticut.
FAU - Kent, Daniel J
AU  - Kent DJ
FAU - Munoz, Angelica A
AU  - Munoz AA
FAU - Melkus, Gail D'Eramo
AU  - Melkus GD
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - J Am Assoc Nurse Pract
JT  - Journal of the American Association of Nurse Practitioners
JID - 101600770
RN  - 0 (Cholesterol, LDL)
RN  - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors)
MH  - Cardiovascular Diseases/diagnosis/etiology/prevention & control
MH  - Cholesterol, LDL/*blood
MH  - Diabetes Mellitus, Type 2/complications/diagnosis/*therapy
MH  - Humans
MH  - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use
MH  - Life Style
MH  - Nurse Practitioners
MH  - Nurse's Role
OTO - NOTNLM
OT  - Diabetes type 2
OT  - lifestyle
OT  - low-density lipoprotein cholesterol
OT  - pharmacotherapy
EDAT- 2013/10/31 06:00
MHDA- 2015/04/09 06:00
CRDT- 2013/10/31 06:00
PHST- 2013/10/31 06:00 [entrez]
PHST- 2013/10/31 06:00 [pubmed]
PHST- 2015/04/09 06:00 [medline]
AID - 10.1002/2327-6924.12053 [doi]
PST - ppublish
SO  - J Am Assoc Nurse Pract. 2013 Sep;25(9):488-94. doi: 10.1002/2327-6924.12053.