PMID- 24177334
OWN - NLM
STAT- MEDLINE
DCOM- 20141031
LR  - 20140219
IS  - 1940-4034 (Electronic)
IS  - 1074-2484 (Linking)
VI  - 19
IP  - 2
DP  - 2014 Mar
TI  - Update on pharmacologic therapy for pulmonary embolism.
PG  - 159-69
LID - 10.1177/1074248413506612 [doi]
AB  - Warfarin, unfractionated heparin (UFH), and low-molecular-weight heparins are 
      anticoagulants that have been used for treatment of pulmonary embolism. Currently 
      approved drugs for treatment of venous thromboembolism include UFH, enoxaparin, 
      dalteparin, fondaparinux, warfarin, and rivaroxaban. The advent of newer oral 
      anticoagulants such as rivaroxaban, dabigatran, and apixaban has provided us with 
      alternative therapeutic options for long-term anticoagulation. This article will 
      give an overview of the various anticoagulant drugs, use in various clinical 
      scenarios, data supporting their clinical use, and recommendations regarding 
      duration of anticoagulant therapy.
FAU - Harikrishnan, Prakash
AU  - Harikrishnan P
AD  - 1Cardiology Division, Westchester Medical Center, New York Medical College, 
      Valhalla, NY, USA.
FAU - Palaniswamy, Chandrasekar
AU  - Palaniswamy C
FAU - Aronow, Wilbert S
AU  - Aronow WS
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20131031
PL  - United States
TA  - J Cardiovasc Pharmacol Ther
JT  - Journal of cardiovascular pharmacology and therapeutics
JID - 9602617
RN  - 0 (Anticoagulants)
RN  - 0 (Fibrinolytic Agents)
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors)
RN  - 5Q7ZVV76EI (Warfarin)
RN  - R16CO5Y76E (Aspirin)
SB  - IM
MH  - Animals
MH  - Anticoagulants/metabolism/*therapeutic use
MH  - Aspirin/metabolism/therapeutic use
MH  - Fibrinolytic Agents/metabolism/*therapeutic use
MH  - Heparin, Low-Molecular-Weight/metabolism/therapeutic use
MH  - Humans
MH  - Hydroxymethylglutaryl-CoA Reductase Inhibitors/metabolism/therapeutic use
MH  - Pulmonary Embolism/*diagnosis/*drug therapy/metabolism
MH  - Warfarin/metabolism/therapeutic use
OTO - NOTNLM
OT  - apixaban
OT  - dabigatran
OT  - pulmonary embolism
OT  - rivaroxaban
OT  - warfarin
EDAT- 2013/11/02 06:00
MHDA- 2014/11/02 06:00
CRDT- 2013/11/02 06:00
PHST- 2013/11/02 06:00 [entrez]
PHST- 2013/11/02 06:00 [pubmed]
PHST- 2014/11/02 06:00 [medline]
AID - 1074248413506612 [pii]
AID - 10.1177/1074248413506612 [doi]
PST - ppublish
SO  - J Cardiovasc Pharmacol Ther. 2014 Mar;19(2):159-69. doi: 
      10.1177/1074248413506612. Epub 2013 Oct 31.