PMID- 24180330
OWN - NLM
STAT- MEDLINE
DCOM- 20150330
LR  - 20190116
IS  - 1029-2403 (Electronic)
IS  - 1026-8022 (Linking)
VI  - 55
IP  - 8
DP  - 2014 Aug
TI  - Advances in umbilical cord blood transplant: a summary of the 11th International 
      Cord Blood Symposium, San Francisco, 6-8 June 2013.
PG  - 1735-8
LID - 10.3109/10428194.2013.837162 [doi]
AB  - The 11th International Cord Blood Symposium was devoted to advances in umbilical 
      cord blood (UCB) research and transplant. Results of cord blood transplant (UCB 
      SCT) for congenital storage disease and hemoglobinopathies are encouraging, but 
      UCB SCT may also be useful for older adults with hematologic malignancies, and 
      UCB cells have potential in regenerative medicine, particularly for neurological 
      disorders, and may serve as excellent targets for gene therapy. UCB donor 
      selection should consider high resolution human leukocyte antigen (HLA) typing, 
      maternal HLA typing and detection of donor specific HLA antibodies. The issue of 
      delayed hematopoietic reconstitution has hamstrung UCB SCT, but is addressed to a 
      large extent by co-infusion of third-party progenitor cells. A number of cell 
      expansion technologies also have great potential. Novel data show more limited 
      benefits of double versus single umbilical cord blood transplant. Advances in 
      quality control (QC) of UCB products and other improvements in cord blood banking 
      technology will further improve the quality of stored UCB products.
FAU - van Besien, Koen
AU  - van Besien K
AD  - Hematology/Oncology, Weill Cornell Medical College , New York, NY , USA.
LA  - eng
PT  - Congress
DEP - 20140402
PL  - United States
TA  - Leuk Lymphoma
JT  - Leukemia & lymphoma
JID - 9007422
SB  - IM
MH  - *Cord Blood Stem Cell Transplantation/methods/standards
MH  - Genetic Diseases, Inborn/therapy
MH  - Genetic Therapy
MH  - Hematologic Neoplasms/therapy
MH  - Humans
MH  - Regenerative Medicine
MH  - Tissue Banks
OTO - NOTNLM
OT  - Basic biology
OT  - adoptive cellular therapies
OT  - clinical results
OT  - cord blood
EDAT- 2013/11/05 06:00
MHDA- 2015/03/31 06:00
CRDT- 2013/11/05 06:00
PHST- 2013/11/05 06:00 [entrez]
PHST- 2013/11/05 06:00 [pubmed]
PHST- 2015/03/31 06:00 [medline]
AID - 10.3109/10428194.2013.837162 [doi]
PST - ppublish
SO  - Leuk Lymphoma. 2014 Aug;55(8):1735-8. doi: 10.3109/10428194.2013.837162. Epub 
      2014 Apr 2.