PMID- 2418204 OWN - NLM STAT- MEDLINE DCOM- 19860306 LR - 20061115 IS - 0315-162X (Print) IS - 0315-162X (Linking) VI - 12 IP - 5 DP - 1985 Oct TI - Antibodies to ribonucleic acids detected by ELISA in systemic lupus erythematosus, systemic sclerosis and rheumatoid arthritis. PG - 928-33 AB - The natural and synthetic antiribonucleic acid antibodies (anti-RNA) are more frequently found in systemic lupus erythematosus (SLE) (80%) than in systemic sclerosis (66%) or in rheumatoid arthritis (RA) (54.5%). SLE sera contain antibodies directed against a broader variety of RNA than systemic sclerosis sera and most RA sera. Fifty-two percent of SLE and 29.2% of systemic sclerosis sera recognized at least 5 of the 7 RNA types studied, whereas RA sera recognized only one or 2. Synthetic antipolynucleotide antibody activities are mainly antipolyriboguanylic-ribocytidylic acid (prG-rC), antipolyriboadenylic-ribouridylic acid (prA-rU) and polyriboadenylic acid (prA) antibody in SLE, antipolyriboguanylic acid (prG) and antipolyribocytidylic acid (prC) antibody in systemic sclerosis and anti-prG-rC, anti-prC antibody in RA. FAU - Costa, O AU - Costa O FAU - Pinatel, K AU - Pinatel K FAU - Monier, J C AU - Monier JC LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Canada TA - J Rheumatol JT - The Journal of rheumatology JID - 7501984 RN - 0 (Autoantibodies) RN - 63231-63-0 (RNA) SB - IM MH - Arthritis, Rheumatoid/immunology MH - Autoantibodies/*analysis MH - Autoimmune Diseases/*immunology MH - Cross Reactions MH - Enzyme-Linked Immunosorbent Assay MH - Humans MH - Lupus Erythematosus, Systemic/immunology MH - RNA/chemical synthesis/*immunology MH - Scleroderma, Systemic/immunology EDAT- 1985/10/01 00:00 MHDA- 1985/10/01 00:01 CRDT- 1985/10/01 00:00 PHST- 1985/10/01 00:00 [pubmed] PHST- 1985/10/01 00:01 [medline] PHST- 1985/10/01 00:00 [entrez] PST - ppublish SO - J Rheumatol. 1985 Oct;12(5):928-33.