PMID- 24188117
OWN - NLM
STAT- MEDLINE
DCOM- 20141217
LR  - 20211021
IS  - 1931-1559 (Electronic)
IS  - 0894-4105 (Print)
IS  - 0894-4105 (Linking)
VI  - 28
IP  - 3
DP  - 2014 May
TI  - Binocular depth perception in individuals at clinical high risk for psychosis: no 
      evidence of dysfunction.
PG  - 366-72
LID - 10.1037/neu0000033 [doi]
AB  - OBJECTIVE: In the last decade the interest in the role of the visual system in 
      schizophrenia has grown, with evidence pointing to dysfunction in bottom-up 
      visual processing that leads to early visual processing deficits. A fundamental 
      component of visual perception is binocular depth perception (BDP), that is, 
      depth perception derived by the difference between the images impressed upon the 
      left and right retina. Two studies reported impaired BDP in schizophrenia and 
      suggested a possible developmental deficit of brain structures involved in early 
      visual processing. The aim of this study was to examine BDP in a young population 
      at clinical high risk (CHR) of developing psychosis to determine whether this 
      dysfunction is present in this potentially prepsychotic period. METHODS: 
      Forty-two CHR participants and 44 healthy controls were assessed using a 
      computerized test of depth perception; a subsample completed a test of 
      stereopsis. The computerized test comprised two trial blocks, with four 
      conditions at increasing level of difficulty, in which participants were asked to 
      discriminate the relative depth of two stimuli simultaneously presented on the 
      screen. RESULTS: BDP was not impaired in the CHR group, whose performance was 
      similar to that of the control group on both measures. For the CHR group 
      performance in both tests was not correlated to positive symptoms. CONCLUSIONS: 
      These results indicate that BDP is preserved in individuals at CHR for psychosis, 
      and impaired BDP should not be considered a vulnerability marker for 
      schizophrenia. Nevertheless future studies should verify BDP's potential power in 
      predicting schizophrenia.
FAU - Barbato, Mariapaola
AU  - Barbato M
AD  - Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary.
FAU - Addington, Jean
AU  - Addington J
AD  - Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary.
LA  - eng
GR  - U01 MH081984/MH/NIMH NIH HHS/United States
PT  - Journal Article
DEP - 20131104
PL  - United States
TA  - Neuropsychology
JT  - Neuropsychology
JID - 8904467
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Case-Control Studies
MH  - Depth Perception/*physiology
MH  - Female
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Neuropsychological Tests
MH  - Photic Stimulation
MH  - *Prodromal Symptoms
MH  - Psychotic Disorders/*physiopathology
MH  - *Telescopes
MH  - Young Adult
PMC - PMC4050980
MID - NIHMS590865
EDAT- 2013/11/06 06:00
MHDA- 2014/12/18 06:00
PMCR- 2015/05/01
CRDT- 2013/11/06 06:00
PHST- 2013/11/06 06:00 [entrez]
PHST- 2013/11/06 06:00 [pubmed]
PHST- 2014/12/18 06:00 [medline]
PHST- 2015/05/01 00:00 [pmc-release]
AID - 2013-38695-001 [pii]
AID - 10.1037/neu0000033 [doi]
PST - ppublish
SO  - Neuropsychology. 2014 May;28(3):366-72. doi: 10.1037/neu0000033. Epub 2013 Nov 4.