PMID- 24189104
OWN - NLM
STAT- MEDLINE
DCOM- 20140813
LR  - 20140109
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 470-471
DP  - 2014 Feb 1
TI  - Plasma concentrations of persistent organic pollutants in the Cree of northern 
      Quebec, Canada: results from the multi-community environment-and-health study.
PG  - 818-28
LID - S0048-9697(13)01192-3 [pii]
LID - 10.1016/j.scitotenv.2013.10.048 [doi]
AB  - Historically, resource development has had negative impacts on the traditional 
      lifestyle of First Nation Cree Communities in the Province of Quebec, Canada. In 
      response to the perceived need for fisheries restoration and for managing health 
      concerns associated with environmental pollutants, the Mercury Program in the 
      James Bay Region of Quebec was reconstituted in 2001 and broadened to include a 
      wider range of chemicals of concern. Based on comprehensive surveys of the nine 
      Cree Territory (Eeyou Istchee) communities in this region during the period 
      2002-2009, blood plasma concentrations are presented of Aroclor 1260, PCB 
      congeners 28, 52, 99, 101, 105, 118, 128, 138, 153, 156, 163, 170, 180, 183, and 
      187, Aldrin, ss-HCH, alpha-Chlordane, gamma-Chlordane, oxy-Chlordane, trans-Nonachlor, 
      cis-Nonachlor, p,p'-DDT, p,p'-DDE, Hexachloro benzene (HCB), Mirex, PBB 153, PBDE 
      47, PBDE 99, PBDE 100, PBDE 153, Toxaphene 26, and Toxaphene 50. The 
      organohalogenated compounds were extracted using solid-phase extraction and 
      cleaned on florisil columns before high resolution HRGC-MS analysis. Principal 
      component analysis (PCA) was used to reduce the large number of contaminant 
      variables into a smaller number of uncorrelated variables. ANOVA identified 
      significant differences between age groups, with the older participants having 
      higher body burdens of legacy lipophilic contaminants, but not for the PBDEs. In 
      certain female age groups, plasma concentrations of PBDEs were observed to be 
      lower than for males; conversely, DDT was higher. Among communities, 
      concentrations were different (p<0.001) for all contaminants. This work provides 
      a baseline for the James Bay Eeyou Istchee communities who, to varying degrees, 
      rely on food and other resources from the land and therefore are at higher risk 
      of increased body burdens of legacy persistent organic pollutants (POPs).
CI  - (c) 2013.
FAU - Liberda, Eric N
AU  - Liberda EN
AD  - School of Occupational and Public Health, Ryerson University, Toronto, ON, 
      Canada. Electronic address: eric.liberda@ryerson.ca.
FAU - Tsuji, Leonard J S
AU  - Tsuji LJ
AD  - Department of Environment and Resource Studies, University of Waterloo, Waterloo, 
      ON, Canada.
FAU - Martin, Ian D
AU  - Martin ID
AD  - Department of Environment and Resource Studies, University of Waterloo, Waterloo, 
      ON, Canada.
FAU - Cote, Suzanne
AU  - Cote S
AD  - Sante publique et pratiques optimales en sante, Centre de Recherche du CHU de 
      Quebec, Quebec, QC, Canada.
FAU - Ayotte, Pierre
AU  - Ayotte P
AD  - Sante publique et pratiques optimales en sante, Centre de Recherche du CHU de 
      Quebec, Quebec, QC, Canada; Laboratoire de toxicologie, INSPQ, 945, Avenue Wolfe, 
      Quebec, QC, Canada.
FAU - Dewailly, Eric
AU  - Dewailly E
AD  - Laboratoire de toxicologie, INSPQ, 945, Avenue Wolfe, Quebec, QC, Canada.
FAU - Nieboer, Evert
AU  - Nieboer E
AD  - Department of Biochemistry and Biomedical Sciences, McMaster University, 
      Hamilton, ON, Canada.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20131102
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Environmental Pollutants)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Environmental Exposure/*analysis/statistics & numerical data
MH  - Environmental Monitoring
MH  - Environmental Pollutants/*blood
MH  - Female
MH  - Humans
MH  - Indians, North American
MH  - Male
MH  - Quebec
MH  - Young Adult
OTO - NOTNLM
OT  - Age variation
OT  - Geographic variation
OT  - Organochlorine pesticides
OT  - PBDEs
OT  - PCBs
OT  - Subarctic First Nation
EDAT- 2013/11/06 06:00
MHDA- 2014/08/15 06:00
CRDT- 2013/11/06 06:00
PHST- 2013/07/25 00:00 [received]
PHST- 2013/10/01 00:00 [revised]
PHST- 2013/10/14 00:00 [accepted]
PHST- 2013/11/06 06:00 [entrez]
PHST- 2013/11/06 06:00 [pubmed]
PHST- 2014/08/15 06:00 [medline]
AID - S0048-9697(13)01192-3 [pii]
AID - 10.1016/j.scitotenv.2013.10.048 [doi]
PST - ppublish
SO  - Sci Total Environ. 2014 Feb 1;470-471:818-28. doi: 
      10.1016/j.scitotenv.2013.10.048. Epub 2013 Nov 2.