PMID- 24195663 OWN - NLM STAT- MEDLINE DCOM- 20141022 LR - 20191210 IS - 1875-5607 (Electronic) IS - 1389-5575 (Linking) VI - 13 IP - 14 DP - 2013 Dec TI - 4-methylamphetamine (4-MA): chemistry, pharmacology and toxicology of a new potential recreational drug. PG - 2097-101 AB - From 2005 to 2012, 236 new substances have been officially notified in European Union via the Early Warning System with an increasing trend from year by year. In October 2009, 4-methylamphetamine (4-MA), an amphetamine derivative, was detected in Belgium and on 14 December 2009 this stimulant was notified to the European Monitoring Centre for Drugs and Drug Addiction. Since its appearance within the recreational drug market, some cases of severe intoxication and deaths have been signaled across Europe. In this paper we summarized the chemical, pharmacological and toxicological information about this new potential recreational drug. FAU - Coppola, M AU - Coppola M FAU - Mondola, R AU - Mondola R AD - Department of Addiction, ASL CN2, Viale Coppino 46, 12051, Alba (CN), Italy. coppolamail@alice.it. LA - eng PT - Journal Article PL - Netherlands TA - Mini Rev Med Chem JT - Mini reviews in medicinal chemistry JID - 101094212 RN - 0 (Central Nervous System Stimulants) RN - 0 (Illicit Drugs) RN - 44RAL3456C (Methamphetamine) SB - IM MH - Animals MH - Central Nervous System Stimulants/analysis/*chemistry/toxicity MH - Drug Monitoring MH - Gas Chromatography-Mass Spectrometry MH - Humans MH - Illicit Drugs/analysis/*chemistry/toxicity MH - Methamphetamine/analysis/*chemistry/toxicity MH - Models, Animal MH - Motor Activity/drug effects MH - Substance-Related Disorders EDAT- 2013/11/08 06:00 MHDA- 2014/10/23 06:00 CRDT- 2013/11/08 06:00 PHST- 2013/06/07 00:00 [received] PHST- 2013/10/07 00:00 [revised] PHST- 2013/10/10 00:00 [accepted] PHST- 2013/11/08 06:00 [entrez] PHST- 2013/11/08 06:00 [pubmed] PHST- 2014/10/23 06:00 [medline] AID - MRMC-EPUB-57241 [pii] AID - 10.2174/13895575113136660106 [doi] PST - ppublish SO - Mini Rev Med Chem. 2013 Dec;13(14):2097-101. doi: 10.2174/13895575113136660106.