PMID- 24198516
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140624
LR  - 20211021
IS  - 1178-6957 (Print)
IS  - 1178-6957 (Electronic)
IS  - 1178-6957 (Linking)
VI  - 3
DP  - 2010 Aug 26
TI  - Hematopoietic stem cell transplantation.
PG  - 105-17
LID - 10.2147/SCCAA.S6815 [doi]
AB  - More than 25,000 hematopoietic stem cell transplantations (HSCTs) are performed 
      each year for the treatment of lymphoma, leukemia, immune-deficiency illnesses, 
      congenital metabolic defects, hemoglobinopathies, and myelodysplastic and 
      myeloproliferative syndromes. Before transplantation, patients receive intensive 
      myeloablative chemoradiotherapy followed by stem cell "rescue." Autologous HSCT 
      is performed using the patient's own hematopoietic stem cells, which are 
      harvested before transplantation and reinfused after myeloablation. Allogeneic 
      HSCT uses human leukocyte antigen (HLA)-matched stem cells derived from a donor. 
      Survival after allogeneic transplantation depends on donor-recipient matching, 
      the graft-versus-host response, and the development of a graft versus leukemia 
      effect. This article reviews the biology of stem cells, clinical efficacy of 
      HSCT, transplantation procedures, and potential complications.
FAU - Hatzimichael, Eleftheria
AU  - Hatzimichael E
AD  - Department of Haematology, Medical School of Ioannina, University of Ioannina, 
      Ioannina, Greece.
FAU - Tuthill, Mark
AU  - Tuthill M
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20100826
PL  - New Zealand
TA  - Stem Cells Cloning
JT  - Stem cells and cloning : advances and applications
JID - 101535817
PMC - PMC3781735
OTO - NOTNLM
OT  - complications
OT  - hematopoietic stem cell transplantation
EDAT- 2010/01/01 00:00
MHDA- 2010/01/01 00:01
PMCR- 2010/08/26
CRDT- 2013/11/08 06:00
PHST- 2013/11/08 06:00 [entrez]
PHST- 2010/01/01 00:00 [pubmed]
PHST- 2010/01/01 00:01 [medline]
PHST- 2010/08/26 00:00 [pmc-release]
AID - sccaa-3-105 [pii]
AID - 10.2147/SCCAA.S6815 [doi]
PST - epublish
SO  - Stem Cells Cloning. 2010 Aug 26;3:105-17. doi: 10.2147/SCCAA.S6815.