PMID- 24201738 OWN - NLM STAT- MEDLINE DCOM- 20150727 LR - 20140913 IS - 1553-3514 (Electronic) IS - 1553-3506 (Linking) VI - 21 IP - 5 DP - 2014 Oct TI - Ligation of the intersphincteric fistula tract (LIFT): a minimally invasive procedure for complex anal fistula: two-year results of a prospective multicentric study. PG - 476-80 LID - 10.1177/1553350613508018 [doi] AB - INTRODUCTION: The surgical management of anal fistulas is still a matter of discussion and no clear recommendations exist. The present study analyses the results of the ligation of the intersphincteric fistula tract (LIFT) technique in treating complex anal fistulas, in particular healing, fecal continence, and recurrence. METHODS: Between October 2010 and February 2012, a total of 26 consecutive patients underwent LIFT. All patients had a primary complex anal fistula and preoperatively all underwent clinical examination, proctoscopy, transanal ultrasonography/magnetic resonance imaging, and were treated with the LIFT procedure. For the purpose of this study, fistulas were classified as complex if any of the following conditions were present: tract crossing more than 30% of the external sphincter, anterior fistula in a woman, recurrent fistula, or preexisting incontinence. Patient's postoperative complications, healing time, recurrence rate, and postoperative continence were recorded during follow-up. RESULTS: The minimum follow-up was 16 months. Five patients required delayed LIFT after previous seton. There were no surgical complications. Primary healing was achieved in 19 patients (73%). Seven patients (27%) had recurrence presenting between 4 and 8 weeks postoperatively and required further surgical treatment. Two of them (29%) had previous insertion of a seton. No patients reported any incontinence postoperatively and we did not observe postoperative continence worsening. CONCLUSION: In our experience, LIFT appears easy to perform, is safe with no surgical complication, has no risk of incontinence, and has a low recurrence rate. These results suggest that LIFT as a minimally invasive technique should be routinely considered for patients affected by complex anal fistula. CI - (c) The Author(s) 2013. FAU - Sileri, Pierpaolo AU - Sileri P AD - Univesity of Rome Tor Vergata, Rome, Italy piersileri@yahoo.com. FAU - Giarratano, Gabriella AU - Giarratano G AD - CdC Madonna delle Grazie, Rome, Italy. FAU - Franceschilli, Luana AU - Franceschilli L AD - Univesity of Rome Tor Vergata, Rome, Italy. FAU - Limura, Elsa AU - Limura E AD - Univesity of Rome Tor Vergata, Rome, Italy. FAU - Perrone, Federico AU - Perrone F AD - Univesity of Rome Tor Vergata, Rome, Italy. FAU - Stazi, Alessandro AU - Stazi A AD - CdC Madonna delle Grazie, Rome, Italy. FAU - Toscana, Claudio AU - Toscana C AD - CdC Madonna delle Grazie, Rome, Italy. FAU - Gaspari, Achille Lucio AU - Gaspari AL AD - Univesity of Rome Tor Vergata, Rome, Italy. LA - eng PT - Journal Article PT - Multicenter Study DEP - 20131106 PL - United States TA - Surg Innov JT - Surgical innovation JID - 101233809 SB - IM MH - Adult MH - Aged MH - Fecal Incontinence MH - Female MH - Humans MH - Ligation/*methods MH - Male MH - Middle Aged MH - Minimally Invasive Surgical Procedures/*methods MH - Prospective Studies MH - Rectal Fistula/epidemiology/*surgery MH - Recurrence MH - Treatment Outcome OTO - NOTNLM OT - (LIFT) OT - anal fistula OT - incontinence OT - ligation of the intersphincteric fistula tract OT - recurrence EDAT- 2013/11/10 06:00 MHDA- 2015/07/28 06:00 CRDT- 2013/11/09 06:00 PHST- 2013/11/09 06:00 [entrez] PHST- 2013/11/10 06:00 [pubmed] PHST- 2015/07/28 06:00 [medline] AID - 1553350613508018 [pii] AID - 10.1177/1553350613508018 [doi] PST - ppublish SO - Surg Innov. 2014 Oct;21(5):476-80. doi: 10.1177/1553350613508018. Epub 2013 Nov 6.