PMID- 24206044
OWN - NLM
STAT- MEDLINE
DCOM- 20150522
LR  - 20181202
IS  - 1365-277X (Electronic)
IS  - 0952-3871 (Linking)
VI  - 27
IP  - 5
DP  - 2014 Oct
TI  - Effects of green tea or green tea extract on insulin sensitivity and glycaemic 
      control in populations at risk of type 2 diabetes mellitus: a systematic review 
      and meta-analysis of randomised controlled trials.
PG  - 501-12
LID - 10.1111/jhn.12181 [doi]
AB  - BACKGROUND: Although the regular consumption of green tea or green tea extract 
      has been considered to improve insulin sensitivity, the reported results are 
      inconsistent. Therefore, we conducted a meta-analysis to evaluate the effect of 
      green tea or green tea extract on insulin sensitivity and glycaemic control in 
      populations at risk of type 2 diabetes mellitus (T2DM). METHODS: Electronic 
      databases, including PUBMED, The Cochrane Library, EMBASE, ISI Web of Knowledge, 
      Chinese Biomedical Literature Database and Chinese Scientific Journals Fulltext 
      Database, were systematically searched to identify randomised controlled trials 
      (RCTs) up to December 2011, supplemented by the Clinicaltrials.gov websites and 
      the reference lists of identified studies. Two reviewers independently selected 
      trials, extracted data, and evaluated the methodological qualities and evidence 
      levels. RESULTS: Seven RCTs involving 510 participants were identified. There was 
      no statistically significant difference between green tea or green tea extract 
      group and placebo group with regard to fasting plasma glucose [standardised mean 
      difference (SMD) 0.04; 95% confidence interval (CI) -0.15 to 0.24], fasting serum 
      insulin (SMD -0.09; 95% CI -0.30 to 0.11), 2-h plasma glucose in the oral glucose 
      tolerance test (OGTT-2 h) (SMD -0.14; 95% CI -0.63 to 0.34), haemoglobin A(1)c (SMD 
      0.10; 95% CI -0.13 to 0.33) and homeostasis model of insulin resistance 
      (HOMA(IR)) index (SMD -0.06; 95% CI -0.35 to 0.23) in participants at risk of 
      T2DM. CONCLUSIONS: The consumption of green tea did not decrease the levels of 
      fasting plasma glucose, fasting serum insulin, OGTT-2 h glucose, haemoglobin A(1)c 
      and HOMA(IR) in populations at risk of T2DM. Larger, longer-term and high-quality 
      RCTs are needed to further definitely determine the effect of green tea or green 
      tea extract on insulin sensitivity and glycaemic control in populations at risk 
      of T2DM.
CI  - (c) 2013 The British Dietetic Association Ltd.
FAU - Wang, X
AU  - Wang X
AD  - Key Laboratory of Endocrinology, Ministry of Health, Department of Endocrinology, 
      Peking Union Medical College Hospital, Peking Union Medical College, Chinese 
      Academy of Medical Sciences, Beijing, China.
FAU - Tian, J
AU  - Tian J
FAU - Jiang, J
AU  - Jiang J
FAU - Li, L
AU  - Li L
FAU - Ying, X
AU  - Ying X
FAU - Tian, H
AU  - Tian H
FAU - Nie, M
AU  - Nie M
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20131108
PL  - England
TA  - J Hum Nutr Diet
JT  - Journal of human nutrition and dietetics : the official journal of the British 
      Dietetic Association
JID - 8904840
RN  - 0 (Plant Extracts)
RN  - 0 (Tea)
SB  - IM
MH  - Diabetes Mellitus, Type 2/diet therapy/epidemiology/metabolism/*prevention & 
      control
MH  - Dietary Supplements
MH  - *Evidence-Based Medicine
MH  - Food Handling
MH  - Humans
MH  - Hyperglycemia/*prevention & control
MH  - Hyperinsulinism/*prevention & control
MH  - *Insulin Resistance
MH  - Oxidation-Reduction
MH  - Plant Extracts/*therapeutic use
MH  - Plant Leaves/chemistry
MH  - Randomized Controlled Trials as Topic
MH  - Risk Factors
MH  - *Tea/chemistry
OTO - NOTNLM
OT  - green tea
OT  - insulin resistance
OT  - meta-analysis
OT  - randomised controlled trials
OT  - type 2 diabetes mellitus
EDAT- 2013/11/12 06:00
MHDA- 2015/05/23 06:00
CRDT- 2013/11/12 06:00
PHST- 2013/11/12 06:00 [entrez]
PHST- 2013/11/12 06:00 [pubmed]
PHST- 2015/05/23 06:00 [medline]
AID - 10.1111/jhn.12181 [doi]
PST - ppublish
SO  - J Hum Nutr Diet. 2014 Oct;27(5):501-12. doi: 10.1111/jhn.12181. Epub 2013 Nov 8.