PMID- 24219063
OWN - NLM
STAT- MEDLINE
DCOM- 20170509
LR  - 20220311
IS  - 1756-185X (Electronic)
IS  - 1756-1841 (Linking)
VI  - 19
IP  - 4
DP  - 2016 Apr
TI  - The association between serum vitamin D Level and disease activity in Thai 
      rheumatoid arthritis patients.
PG  - 355-61
LID - 10.1111/1756-185X.12222 [doi]
AB  - BACKGROUND: Serum vitamin D level was inversely associated with the risk of 
      developing new onset rheumatoid arthritis (RA) and disease activity, but some 
      conflicting results have been reported. OBJECTIVE: To examine the serum vitamin D 
      status in Thai RA patients and possible independent factors affecting serum 25 
      hydroxyvitamin vitamin D (25(OH)D) and the associations of serum 25(OH)D level 
      and the disease activity and functional status in Thai RA patients. METHODS: A 
      cross-sectional study was performed in 239 Thai RA patients. The blood levels of 
      25(OH)D2 and D3 were measured by chemiluminescent immunoassay. Disease activity 
      was assessed according to tender and swollen joint counts, erythrocyte 
      sedimentation rate (ESR), visual analog scale for global patient assessment, 
      Disease Activity Score-28 (DAS-28) and Thai Health Assessment Questionnaire (Thai 
      HAQ). RESULT: The mean vitamin D level was 28.79 ng/mL. There were no 
      associations between 25(OH)D levels and number of tender and swollen joint 
      counts, DAS-28 score, HAQ score or rheumatoid factor (RF) and/or anti-cyclic 
      citrulinated peptide (CCP) positivity. After multivariated analysis, Bangkok 
      residents, non-farmer, obesity and non-vitamin D supplementation were the 
      predictors for vitamin D insufficiency in Thai patients with RA. CONCLUSION: 
      There are no associations of serum 25(OH)D levels with disease activity or 
      functional status in Thai RA patients. The factors associated with vitamin D 
      insufficiency are Bangkok resident, non-farmer, obesity and not taking vitamin D 
      supplementation.
CI  - (c) 2013 Asia Pacific League of Associations for Rheumatology and Wiley Publishing 
      Asia Pty Ltd.
FAU - Pakchotanon, Rattapol
AU  - Pakchotanon R
AD  - Rheumatic Disease Unit, Department of Medicine, Phramongkutklao Hospital, 
      Bangkok, Thailand.
FAU - Chaiamnuay, Sumapa
AU  - Chaiamnuay S
AD  - Rheumatic Disease Unit, Department of Medicine, Phramongkutklao Hospital, 
      Bangkok, Thailand.
FAU - Narongroeknawin, Pongthorn
AU  - Narongroeknawin P
AD  - Rheumatic Disease Unit, Department of Medicine, Phramongkutklao Hospital, 
      Bangkok, Thailand.
FAU - Asavatanabodee, Paijit
AU  - Asavatanabodee P
AD  - Rheumatic Disease Unit, Department of Medicine, Phramongkutklao Hospital, 
      Bangkok, Thailand.
LA  - eng
PT  - Journal Article
DEP - 20131113
PL  - England
TA  - Int J Rheum Dis
JT  - International journal of rheumatic diseases
JID - 101474930
RN  - 0 (Biomarkers)
RN  - 1406-16-2 (Vitamin D)
RN  - A288AR3C9H (25-hydroxyvitamin D)
SB  - IM
MH  - Aged
MH  - Arthritis, Rheumatoid/*blood/diagnosis/epidemiology
MH  - Biomarkers/blood
MH  - Cross-Sectional Studies
MH  - Dietary Supplements
MH  - Female
MH  - Health Status Indicators
MH  - Humans
MH  - Immunoassay
MH  - Male
MH  - Middle Aged
MH  - Obesity/epidemiology
MH  - Occupations
MH  - Prevalence
MH  - Protective Factors
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
MH  - Thailand/epidemiology
MH  - Urban Health
MH  - Vitamin D/*analogs & derivatives/blood/therapeutic use
MH  - Vitamin D Deficiency/*blood/diagnosis/epidemiology
OTO - NOTNLM
OT  - Thai
OT  - disease activity
OT  - obesity
OT  - rheumatoid arthritis
OT  - vitamin D
EDAT- 2013/11/14 06:00
MHDA- 2017/05/10 06:00
CRDT- 2013/11/14 06:00
PHST- 2013/11/14 06:00 [entrez]
PHST- 2013/11/14 06:00 [pubmed]
PHST- 2017/05/10 06:00 [medline]
AID - 10.1111/1756-185X.12222 [doi]
PST - ppublish
SO  - Int J Rheum Dis. 2016 Apr;19(4):355-61. doi: 10.1111/1756-185X.12222. Epub 2013 
      Nov 13.