PMID- 24229557
OWN - NLM
STAT- MEDLINE
DCOM- 20140710
LR  - 20211021
IS  - 1469-2198 (Electronic)
IS  - 0954-5794 (Print)
IS  - 0954-5794 (Linking)
VI  - 25
IP  - 4 Pt 1
DP  - 2013 Nov
TI  - Reciprocal social behavior in youths with psychotic illness and those at clinical 
      high risk.
PG  - 1187-97
LID - 10.1017/S095457941300045X [doi]
AB  - Youths at clinical high risk (CHR) for psychosis typically exhibit significant 
      social dysfunction. However, the specific social behaviors associated with 
      psychosis risk have not been well characterized. We administer the Social 
      Responsiveness Scale (SRS), a measure of autistic traits that examines reciprocal 
      social behavior, to the parents of 117 adolescents (61 CHR individuals, 20 
      age-matched adolescents with a psychotic disorder [AOP], and 36 healthy controls) 
      participating in a longitudinal study of psychosis risk. AOP and CHR individuals 
      have significantly elevated SRS scores relative to healthy controls, indicating 
      more severe social deficits. Mean scores for AOP and CHR youths are typical of 
      scores obtained in individuals with high functioning autism (Constantino & 
      Gruber, 2005). SRS scores are significantly associated with concurrent real-world 
      social functioning in both clinical groups. Finally, baseline SRS scores 
      significantly predict social functioning at follow-up (an average of 7.2 months 
      later) in CHR individuals, over and above baseline social functioning measures (p 
      < .009). These findings provide novel information regarding impairments in 
      domains critical for adolescent social development, because CHR individuals and 
      those with overt psychosis show marked deficits in reciprocal social behavior. 
      Further, the SRS predicts subsequent real-world social functioning in CHR youth, 
      suggesting that this measure may be useful for identifying targets of treatment 
      in psychosocial interventions.
FAU - Jalbrzikowski, Maria
AU  - Jalbrzikowski M
AD  - University of California, Los Angeles.
FAU - Krasileva, Kate E
AU  - Krasileva KE
FAU - Marvin, Sarah
AU  - Marvin S
FAU - Zinberg, Jamie
AU  - Zinberg J
FAU - Andaya, Angielette
AU  - Andaya A
FAU - Bachman, Peter
AU  - Bachman P
FAU - Cannon, Tyrone D
AU  - Cannon TD
FAU - Bearden, Carrie E
AU  - Bearden CE
LA  - eng
GR  - K23 MH074644/MH/NIMH NIH HHS/United States
GR  - MH65079/MH/NIMH NIH HHS/United States
GR  - R01 MH065079/MH/NIMH NIH HHS/United States
GR  - K23MH74644/MH/NIMH NIH HHS/United States
GR  - P50 MH066286/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Dev Psychopathol
JT  - Development and psychopathology
JID - 8910645
SB  - IM
MH  - Adolescent
MH  - Female
MH  - Humans
MH  - Male
MH  - Neuropsychological Tests
MH  - Psychotic Disorders/*psychology
MH  - Risk
MH  - *Social Adjustment
MH  - *Social Behavior
PMC - PMC4416482
MID - NIHMS618504
EDAT- 2013/11/16 06:00
MHDA- 2014/07/11 06:00
PMCR- 2015/05/01
CRDT- 2013/11/16 06:00
PHST- 2013/11/16 06:00 [entrez]
PHST- 2013/11/16 06:00 [pubmed]
PHST- 2014/07/11 06:00 [medline]
PHST- 2015/05/01 00:00 [pmc-release]
AID - S095457941300045X [pii]
AID - 10.1017/S095457941300045X [doi]
PST - ppublish
SO  - Dev Psychopathol. 2013 Nov;25(4 Pt 1):1187-97. doi: 10.1017/S095457941300045X.