PMID- 24231020
OWN - NLM
STAT- MEDLINE
DCOM- 20140206
LR  - 20220410
IS  - 0964-7058 (Print)
IS  - 0964-7058 (Linking)
VI  - 22
IP  - 4
DP  - 2013
TI  - Prevalence and determinants of hyperuricemia in type 2 diabetes mellitus patients 
      with central obesity in Guangdong Province in China.
PG  - 590-8
LID - 10.6133/apjcn.2013.22.4.16 [doi]
AB  - This study investigated the prevalence and determinants of hyperuricemia in 
      Chinese type 2 diabetes mellitus (T2DM) patients with central obesity. A 
      multicentric hospital-based cross-sectional study was carried out in Guangdong 
      Province between August 2011 and March 2012. At each hospital, Chinese T2DM 
      patients with central obesity who were aged over 20 years, whose serum uric acid 
      levels were measured, and who had lived in Guangdong Province for >=1 year, were 
      recruited. Hyperuricemia was defined as serum uric acid >420 mumol/L in men and 
      >360 mumol/L in women. Binary logistic regression was used to assess associated 
      risk factors for hyperu-ricemia. A total of 2,917 T2DM patients with central 
      obesity took part. The overall prevalence of hyperuricemia was 32.6% (36.1% for 
      women, 28.4% for men). Binary logistic regression analyses demonstrated that 
      women (OR: 1.576; 95% confidence interval (CI): 1.231, 2.018), high BMI (OR: 
      1.228; 95% CI: 1.094, 1.379), waist cir-cumference (OR: 1.135; 95% CI: 1.009, 
      1.276), hypertension (OR: 1.603; 95% CI: 1.263, 2.035), high total cho-lesterol 
      (OR: 1.133; 95% CI: 1.002, 1.281), triglycerides (OR: 1.134; 95% CI: 1.069, 
      1.203), low HDL-cholesterol (OR: 0.820; 95% CI: 0.677, 0.995) and low estimated 
      glomerular filtration rate (OR: 0.840; 95% CI: 0.815, 0.866) were risk factors 
      associated with hyperuricemia. Hyperuricemia is prevalent in Chinese T2DM 
      patients with central obesity and is significantly positively associated with 
      women, cardiovascular risk factors such as obesity, hypertension and 
      dyslipidemia, and low eGFR.
FAU - Wang, Jiao
AU  - Wang J
AD  - Department of Endocrinology, Zhujiang Hospital, Southern Medical University, 253# 
      industry road, 510282, Guangzhou, Guangdong, China. dehongcaizj@163.com.
FAU - Chen, Rong-Ping
AU  - Chen RP
FAU - Lei, Lei
AU  - Lei L
FAU - Song, Qing-Qing
AU  - Song QQ
FAU - Zhang, Ru-Yi
AU  - Zhang RY
FAU - Li, Yan-Bing
AU  - Li YB
FAU - Yang, Chuan
AU  - Yang C
FAU - Lin, Shao-Da
AU  - Lin SD
FAU - Chen, Li-shu
AU  - Chen LS
FAU - Wang, Yu-Lin
AU  - Wang YL
FAU - Zhao, Fan
AU  - Zhao F
FAU - Liang, Gan-Xiong
AU  - Liang GX
FAU - Hu, Bao-Chun
AU  - Hu BC
FAU - Lin, Jian-Cai
AU  - Lin JC
FAU - Cai, De-Hong
AU  - Cai DH
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Asia Pac J Clin Nutr
JT  - Asia Pacific journal of clinical nutrition
JID - 9440304
RN  - 0 (Lipids)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Body Mass Index
MH  - China/epidemiology
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Female
MH  - Hospitals
MH  - Humans
MH  - Hyperuricemia/*epidemiology/etiology
MH  - Lipids/blood
MH  - Male
MH  - Middle Aged
MH  - Obesity, Abdominal/*complications
MH  - Risk Factors
MH  - Sex Factors
MH  - Waist Circumference
EDAT- 2013/11/16 06:00
MHDA- 2014/02/07 06:00
CRDT- 2013/11/16 06:00
PHST- 2013/11/16 06:00 [entrez]
PHST- 2013/11/16 06:00 [pubmed]
PHST- 2014/02/07 06:00 [medline]
AID - 10.6133/apjcn.2013.22.4.16 [doi]
PST - ppublish
SO  - Asia Pac J Clin Nutr. 2013;22(4):590-8. doi: 10.6133/apjcn.2013.22.4.16.