PMID- 24232828 OWN - NLM STAT- MEDLINE DCOM- 20140609 LR - 20240324 IS - 2314-6141 (Electronic) IS - 2314-6133 (Print) VI - 2013 DP - 2013 TI - Interactive multigrid refinement for deformable image registration. PG - 532936 LID - 10.1155/2013/532936 [doi] LID - 532936 AB - Deformable image registration is the spatial mapping of corresponding locations between images and can be used for important applications in radiotherapy. Although numerous methods have attempted to register deformable medical images automatically, such as salient-feature-based registration (SFBR), free-form deformation (FFD), and demons, no automatic method for registration is perfect, and no generic automatic algorithm has shown to work properly for clinical applications due to the fact that the deformation field is often complex and cannot be estimated well by current automatic deformable registration methods. This paper focuses on how to revise registration results interactively for deformable image registration. We can manually revise the transformed image locally in a hierarchical multigrid manner to make the transformed image register well with the reference image. The proposed method is based on multilevel B-spline to interactively revise the deformable transformation in the overlapping region between the reference image and the transformed image. The resulting deformation controls the shape of the transformed image and produces a nice registration or improves the registration results of other registration methods. Experimental results in clinical medical images for adaptive radiotherapy demonstrated the effectiveness of the proposed method. FAU - Zhou, Wu AU - Zhou W AD - Shenzhen Key Laboratory for Low-Cost Healthcare, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. FAU - Xie, Yaoqin AU - Xie Y LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20131022 PL - United States TA - Biomed Res Int JT - BioMed research international JID - 101600173 SB - IM MH - Algorithms MH - Humans MH - *Image Processing, Computer-Assisted MH - Male MH - Prostate/*diagnostic imaging MH - *Tomography, X-Ray Computed PMC - PMC3819831 EDAT- 2013/11/16 06:00 MHDA- 2014/06/10 06:00 PMCR- 2013/10/22 CRDT- 2013/11/16 06:00 PHST- 2013/06/17 00:00 [received] PHST- 2013/09/05 00:00 [accepted] PHST- 2013/11/16 06:00 [entrez] PHST- 2013/11/16 06:00 [pubmed] PHST- 2014/06/10 06:00 [medline] PHST- 2013/10/22 00:00 [pmc-release] AID - 10.1155/2013/532936 [doi] PST - ppublish SO - Biomed Res Int. 2013;2013:532936. doi: 10.1155/2013/532936. Epub 2013 Oct 22.