PMID- 24234818
OWN - NLM
STAT- MEDLINE
DCOM- 20140624
LR  - 20211021
IS  - 1534-3081 (Electronic)
IS  - 1534-3081 (Linking)
VI  - 17
IP  - 12
DP  - 2013 Dec
TI  - Does exercise make migraines worse and tension type headaches better?
PG  - 380
LID - 10.1007/s11916-013-0380-5 [doi]
AB  - Many non-pharmacological treatments have been implicated in the treatment of 
      primary headache, with exercise being a common recommendation. In this review we 
      first provide an overview of the relationship between exercise and primary 
      headaches. We then review the physiology of pain modulation, with focus on the 
      endogenous opioids, endocannabinoids, and neuropeptides calcitonin gene-related 
      peptide (CGRP) and brain-derived neurotrophic factor (BDNF), and their 
      associations with primary headache and exercise. Finally, we summarize current 
      literature evaluating effects of exercise on primary headache in an effort to 
      understand the benefits and disadvantages of exercise in primary headaches.
FAU - Hindiyeh, Nada Ahmad
AU  - Hindiyeh NA
AD  - Stanford University School of Medicine, 291 Campus Drive Rm LK3C02, Li Ka Shing 
      Building, 3rd floor, Dean's Office, MC 5216, Stanford, CA, 94305-5101, USA, 
      nhindiye@stanford.edu.
FAU - Krusz, John Claude
AU  - Krusz JC
FAU - Cowan, Robert Paul
AU  - Cowan RP
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Pain Headache Rep
JT  - Current pain and headache reports
JID - 100970666
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 0 (Endocannabinoids)
RN  - 0 (Receptors, Opioid)
RN  - JHB2QIZ69Z (Calcitonin Gene-Related Peptide)
SB  - IM
MH  - Acute Disease
MH  - Brain-Derived Neurotrophic Factor/metabolism
MH  - Calcitonin Gene-Related Peptide/metabolism
MH  - Endocannabinoids/metabolism
MH  - *Exercise
MH  - Female
MH  - Headache/physiopathology
MH  - Humans
MH  - Male
MH  - Migraine Disorders/*etiology/metabolism/*physiopathology
MH  - Receptors, Opioid/metabolism
MH  - Tension-Type Headache/metabolism/*physiopathology/therapy
EDAT- 2013/11/16 06:00
MHDA- 2014/06/25 06:00
CRDT- 2013/11/16 06:00
PHST- 2013/11/16 06:00 [entrez]
PHST- 2013/11/16 06:00 [pubmed]
PHST- 2014/06/25 06:00 [medline]
AID - 10.1007/s11916-013-0380-5 [doi]
PST - ppublish
SO  - Curr Pain Headache Rep. 2013 Dec;17(12):380. doi: 10.1007/s11916-013-0380-5.