PMID- 24243575
OWN - NLM
STAT- MEDLINE
DCOM- 20150701
LR  - 20220309
IS  - 1522-2586 (Electronic)
IS  - 1053-1807 (Linking)
VI  - 40
IP  - 6
DP  - 2014 Dec
TI  - Rapid single-breath-hold 3D late gadolinium enhancement cardiac MRI using a 
      stack-of-spirals acquisition.
PG  - 1496-502
LID - 10.1002/jmri.24494 [doi]
AB  - PURPOSE: To develop a rapid single-breath-hold 3D late gadolinium enhancement 
      (LGE) magnetic resonance imaging (MRI) method, and demonstrate its feasibility in 
      cardiac patients. MATERIALS AND METHODS: An inversion recovery dual-density 3D 
      stack-of-spirals imaging sequence was developed. The spiral acquisition was 
      2-fold accelerated by self-consistent parallel imaging reconstruction (SPIRiT), 
      which resulted in a total scan time of 12 heartbeats. Field map-based linear 
      off-resonance correction was incorporated to the SPIRiT reconstruction. The 3D 
      spiral LGE scans were performed in 15 patients who were referred for clinically 
      ordered cardiac MR examinations that included the standard 2D multislice LGE 
      imaging. Image sharpness and overall quality were qualitatively assessed based on 
      5-point scales. RESULTS: Scar-induced hyper-LGE was identified in 4 out of the 15 
      patients by both 3D spiral and 2D multislice LGE tests. On average over all 
      datasets (n = 15), the image sharpness scores were 3.9 (3D spiral) and 4.0 (2D 
      multislice), and the image quality scores were 4.1 (3D spiral) and 4.0 (2D 
      multislice) with no significant difference in both metrics (paired t-test; P > 
      0.1). The average scar contrast enhancement ratios were 0.72 and 0.75 in 3D and 
      2D images, respectively (n = 4). The average difference of fractional scar 
      volumes measured in 3D and 2D images was 4.3% (n = 3). CONCLUSION: 
      Stack-of-spiral acquisition combined with non-Cartesian SPIRiT parallel imaging 
      enables rapid 3D LGE MRI in a 12 heartbeat-long breath-hold.J.
CI  - (c) 2013 Wiley Periodicals, Inc.
FAU - Shin, Taehoon
AU  - Shin T
AD  - Department of Electrical Engineering, Stanford University, Stanford, California, 
      USA.
FAU - Lustig, Michael
AU  - Lustig M
FAU - Nishimura, Dwight G
AU  - Nishimura DG
FAU - Hu, Bob S
AU  - Hu BS
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20131115
PL  - United States
TA  - J Magn Reson Imaging
JT  - Journal of magnetic resonance imaging : JMRI
JID - 9105850
RN  - 0 (Contrast Media)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - *Artifacts
MH  - *Breath Holding
MH  - Contrast Media/administration & dosage
MH  - Feasibility Studies
MH  - Humans
MH  - Image Enhancement/*methods
MH  - Image Interpretation, Computer-Assisted/*methods
MH  - Imaging, Three-Dimensional/*methods
MH  - Magnetic Resonance Imaging, Cine/*methods
MH  - Male
MH  - Myocardial Infarction/*pathology
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Signal Processing, Computer-Assisted
OTO - NOTNLM
OT  - 3D late gadolinium enhancement (LGE) MRI
OT  - parallel imaging reconstruction
OT  - stack-of-spirals imaging
EDAT- 2013/11/19 06:00
MHDA- 2015/07/02 06:00
CRDT- 2013/11/19 06:00
PHST- 2013/06/01 00:00 [received]
PHST- 2013/10/08 00:00 [accepted]
PHST- 2013/11/19 06:00 [entrez]
PHST- 2013/11/19 06:00 [pubmed]
PHST- 2015/07/02 06:00 [medline]
AID - 10.1002/jmri.24494 [doi]
PST - ppublish
SO  - J Magn Reson Imaging. 2014 Dec;40(6):1496-502. doi: 10.1002/jmri.24494. Epub 2013 
      Nov 15.