PMID- 24250505 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20131119 LR - 20211021 IS - 1735-0328 (Print) IS - 1726-6890 (Electronic) IS - 1726-6882 (Linking) VI - 11 IP - 3 DP - 2012 Summer TI - Solid-Phase Extraction and Simultaneous Determination of Tetracycline Residues in Edible Cattle Tissues Using an HPLC-FL Method. PG - 781-7 AB - In this assay, edible cattle tissues from local markets of Ardabil, a Province of Iran, were examined for residues of tetracycline antibiotics (tetracycline, oxytetracycline and chlortetracycline). In total, 110 samples of triceps, gluteal muscle, diaphragm, kidney and liver were randomly obtained from the local markets of the city of Ardabil. Solid-phase extraction (SPE) and high-performance liquid chromatography (HPLC) methods were used to extract and analyze tetracycline antibiotic (TC) residues, respectively. The mean amount of total TC residues in all tested samples was 226.3 +/- 112.5 ng/g and the mean amount of the total TC residues in triceps, gluteal muscle, diaphragm, kidney and liver samples were 176.3 +/- 46.8, 405.3 +/- 219.6, 96.8 +/- 26.9, 672.4 +/- 192.0 and 651.3 +/- 210.1 ng/g, respectively. Additionally, 25.8% of muscle samples, 31.8% of liver samples and 22.7% of kidney samples contained amounts of TC residues beyond the maximum residue limit (MRLs). To reduce the TC residues found in edible cattle tissues, regulatory authorities should ensure that the cattle would undergo the proper withdrawal period from TCs before the slaughtering. FAU - Mesgari Abbasi, Mehran AU - Mesgari Abbasi M AD - Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. FAU - Nemati, Mahboob AU - Nemati M FAU - Babaei, Hossein AU - Babaei H FAU - Ansarin, Masoud AU - Ansarin M FAU - Nourdadgar, Ashraf-O-Sadat AU - Nourdadgar AO LA - eng PT - Journal Article PL - Netherlands TA - Iran J Pharm Res JT - Iranian journal of pharmaceutical research : IJPR JID - 101208407 PMC - PMC3813112 OTO - NOTNLM OT - HPLC OT - Kidney OT - Liver OT - Meat OT - Tetracycline EDAT- 2012/07/01 00:00 MHDA- 2012/07/01 00:01 PMCR- 2012/06/01 CRDT- 2013/11/20 06:00 PHST- 2013/11/20 06:00 [entrez] PHST- 2012/07/01 00:00 [pubmed] PHST- 2012/07/01 00:01 [medline] PHST- 2012/06/01 00:00 [pmc-release] AID - ijpr-11-781 [pii] PST - ppublish SO - Iran J Pharm Res. 2012 Summer;11(3):781-7.