PMID- 24274028
OWN - NLM
STAT- MEDLINE
DCOM- 20150513
LR  - 20211021
IS  - 1756-0500 (Electronic)
IS  - 1756-0500 (Linking)
VI  - 6
DP  - 2013 Nov 26
TI  - Relationship between clinically assessed heart failure severity and the Tei index 
      in Nigerian patients.
PG  - 488
LID - 10.1186/1756-0500-6-488 [doi]
AB  - BACKGROUND: The Tei index is a Doppler-derived myocardial performance index. It 
      is a measure of the combined systolic and diastolic myocardial performance of 
      both the left and right ventricles. The incidence of heart failure (HF) is 
      increasing globally, and its severity can be clinically assessed using the New 
      York Heart Association (NYHA) functional classification and more objectively 
      using echocardiographic assessment of systolic and diastolic functions. Thus, a 
      measure of the combined systolic and diastolic myocardial performance could be a 
      useful predictor of the severity of the clinical status of patients with HF. 
      RESULTS: Seventy-five newly presenting patients with HF of NYHA class II to IV 
      and 60 normal controls were consecutively recruited. Using conventional 
      two-dimensional and Doppler echocardiography techniques, the left ventricular 
      parameters assessed were the isovolumic relaxation time (IVRT), isovolumic 
      contraction time (IVCT), ejection time (ET), ejection fraction (EF), and 
      end-diastolic volume (EDV). The Tei index was determined using the formula 
      IVCT + IVRT/ET. The mean Tei index of patients was significantly higher than that 
      of controls (0.884 +/- 0.321 vs. 0.842 +/- 0.14; p < 0.001). The Tei index ranged 
      from 0.33 to 1.94 in patients and from 0.56 to 1.24 in controls. The mean EF was 
      lower in patients than in controls (50.47% +/- 19.01% vs. 68.35% +/- 7.75%; p = 
      0.001). The mean EDV was higher in patients than in controls (171.39 +/- 100.96 vs. 
      94.15 +/- 28.54; p < 0.001). Comparison of the mean Tei indices of patients with HF 
      of NYHA classes II, III, and IV showed statistically significant differences 
      among all three groups (p < 0.001). CONCLUSIONS: The Tei index seems to be a 
      clinically relevant indicator of cardiac function. It is reflective of the 
      severity of HF as clinically assessed using the NYHA functional classification in 
      patients with HF.
FAU - Ogunmola, Olarinde Jeffrey
AU  - Ogunmola OJ
AD  - Cardiac Centre, Department of Internal Medicine, Federal Medical Centre, P,M,B, 
      201, Ido Ekiti, Ekiti State, Nigeria. joogunmola@yahoo.com.
FAU - Akintomide, Anthony Olubunmi
AU  - Akintomide AO
FAU - Olamoyegun, Adeyemi Michael
AU  - Olamoyegun AM
LA  - eng
PT  - Journal Article
DEP - 20131126
PL  - England
TA  - BMC Res Notes
JT  - BMC research notes
JID - 101462768
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Case-Control Studies
MH  - Echocardiography, Doppler
MH  - Female
MH  - Heart Failure/diagnostic imaging/*physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nigeria
MH  - *Severity of Illness Index
MH  - Young Adult
PMC - PMC4222090
EDAT- 2013/11/28 06:00
MHDA- 2015/05/15 06:00
PMCR- 2013/11/26
CRDT- 2013/11/27 06:00
PHST- 2013/06/12 00:00 [received]
PHST- 2013/11/23 00:00 [accepted]
PHST- 2013/11/27 06:00 [entrez]
PHST- 2013/11/28 06:00 [pubmed]
PHST- 2015/05/15 06:00 [medline]
PHST- 2013/11/26 00:00 [pmc-release]
AID - 1756-0500-6-488 [pii]
AID - 10.1186/1756-0500-6-488 [doi]
PST - epublish
SO  - BMC Res Notes. 2013 Nov 26;6:488. doi: 10.1186/1756-0500-6-488.