PMID- 24275845 OWN - NLM STAT- MEDLINE DCOM- 20140930 LR - 20161125 IS - 1545-7222 (Electronic) IS - 0895-0172 (Linking) VI - 26 IP - 1 DP - 2014 Winter TI - Improved outcomes using brain SPECT-guided treatment versus treatment-as-usual in community psychiatric outpatients: a retrospective case-control study. PG - 51-6 LID - 10.1176/appi.neuropsych.12100238 [doi] AB - Brain single-photon emission computed tomography (SPECT) scans indirectly show functional activity via measurement of regional cerebral blood flow. Thirty patients at a community-based psychiatric clinic underwent brain SPECT scans. Changes in scoring of before-treatment and after-treatment scans correlated well with changes in patient Global Assessment of Functioning (GAF) scores before treatment and after treatment. Patients were retrospectively matched with controls with similar diagnoses and pretreatment GAF scores, and those who underwent SPECT-guided treatment improved significantly more than the control patients. FAU - Thornton, John F AU - Thornton JF FAU - Schneider, Howard AU - Schneider H FAU - McLean, Mary K AU - McLean MK FAU - van Lierop, Muriel J AU - van Lierop MJ FAU - Tarzwell, Robert AU - Tarzwell R LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Neuropsychiatry Clin Neurosci JT - The Journal of neuropsychiatry and clinical neurosciences JID - 8911344 RN - 0 (ethyl cysteinate dimer) RN - 48TCX9A1VT (Cystine) SB - IM MH - Brain/*diagnostic imaging/pathology MH - Case-Control Studies MH - Cystine/analogs & derivatives MH - Female MH - Hospitals, Psychiatric MH - Humans MH - Imaging, Three-Dimensional MH - Male MH - Mental Disorders/*diagnostic imaging/*therapy MH - Middle Aged MH - Outpatients MH - Psychiatric Status Rating Scales MH - Residence Characteristics MH - Retrospective Studies MH - Tomography, Emission-Computed, Single-Photon/*methods MH - *Treatment Outcome EDAT- 2013/11/28 06:00 MHDA- 2014/10/01 06:00 CRDT- 2013/11/27 06:00 PHST- 2013/11/27 06:00 [entrez] PHST- 2013/11/28 06:00 [pubmed] PHST- 2014/10/01 06:00 [medline] AID - 1785746 [pii] AID - 10.1176/appi.neuropsych.12100238 [doi] PST - ppublish SO - J Neuropsychiatry Clin Neurosci. 2014 Winter;26(1):51-6. doi: 10.1176/appi.neuropsych.12100238.