PMID- 24278271
OWN - NLM
STAT- MEDLINE
DCOM- 20140923
LR  - 20211021
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 8
IP  - 11
DP  - 2013
TI  - Close correlation between season of birth and the prevalence of bronchial asthma 
      in a Taiwanese population.
PG  - e80285
LID - 10.1371/journal.pone.0080285 [doi]
LID - e80285
AB  - BACKGROUND: Bronchial asthma (BA), atopic dermatitis (AD), and allergic rhinitis 
      (AR) are common allergic diseases. Environmental factors were indicated to 
      influence the development of allergic diseases. OBJECTIVE: To evaluate the 
      correlation between the month of birth and the prevalence of allergic diseases in 
      Taiwan. METHODS: Data from 104,455 children were collected from the National 
      Insurance Research Database of Taiwan. Subjects were identified by at least two 
      service claims for ambulatory care or one claim for inpatient care. All of the 
      enrolled patients were aged 7 approximately 15 years in 2010. In a bio-clinical data analysis, 
      total immunoglobulin E (IgE) and ImmunoCAP allergen data (CAP) from mothers and 
      infants were collected in a medical center in Taiwan. Correlations between 
      children's allergic factors and the season of birth were assessed. RESULTS: A 
      significant difference in the prevalence of BA according to the month of birth 
      (Chi(2) = 18.2, p<0.001) was found in the Taiwanese population. The fewest 
      schoolchildren with were born in May (7.21%), and the most were born in October 
      (10.59%). However, no tendency for the prevalence of AD (Chi(2) = 4.6, P = 0.204) 
      or AR (Chi(2) = 4.3 P = 0.229) was found. In addition, we found that children born 
      in autumn (August to October) had a higher prevalence of BA compared to those 
      born in spring (February to April) (odds ratio: 1.13; 95% confidence interval: 
      1.05 approximately 1.21). In a bio-clinical data study, markers of maternal and childhood 
      allergies including IgE and CAP were detected in a risk analysis section. 
      Children who were born in autumn had higher levels of CAP and total IgE. 
      CONCLUSIONS: The findings of this study showed that the month of birth was 
      closely correlated with the prevalence of BA and higher levels of CAP and IgE.
FAU - Chang, Wei-Chiao
AU  - Chang WC
AD  - Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, 
      Taipei, Taiwan ; Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung 
      Medical University, Kaohsiung, Taiwan ; Department of Pharmacy, Taipei Medical 
      University-Wan Fang Hospital, Taipei, Taiwan ; Master Program for Clinical 
      Pharmacogenomics and Pharmacoproteomics, School of Pharmacy, Taipei Medical 
      University, Taipei, Taiwan.
FAU - Yang, Kuender D
AU  - Yang KD
FAU - Wu, Man-Tzu Marcie
AU  - Wu MT
FAU - Wen, Ya-Feng
AU  - Wen YF
FAU - Hsi, Edward
AU  - Hsi E
FAU - Chang, Jen-Chieh
AU  - Chang JC
FAU - Lin, You-Meei
AU  - Lin YM
FAU - Kuo, Ho-Chang
AU  - Kuo HC
FAU - Chang, Wei-Pin
AU  - Chang WP
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20131120
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Asthma/*epidemiology
MH  - Humans
MH  - Prevalence
MH  - *Seasons
MH  - Taiwan/epidemiology
PMC - PMC3835889
COIS- Competing Interests: The authors have declared that no competing interests exist.
EDAT- 2013/11/28 06:00
MHDA- 2014/09/24 06:00
PMCR- 2013/11/20
CRDT- 2013/11/27 06:00
PHST- 2012/11/13 00:00 [received]
PHST- 2013/10/03 00:00 [accepted]
PHST- 2013/11/27 06:00 [entrez]
PHST- 2013/11/28 06:00 [pubmed]
PHST- 2014/09/24 06:00 [medline]
PHST- 2013/11/20 00:00 [pmc-release]
AID - PONE-D-12-37578 [pii]
AID - 10.1371/journal.pone.0080285 [doi]
PST - epublish
SO  - PLoS One. 2013 Nov 20;8(11):e80285. doi: 10.1371/journal.pone.0080285. 
      eCollection 2013.