PMID- 24278518
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20131126
LR  - 20211021
IS  - 1976-8257 (Print)
IS  - 2234-2753 (Electronic)
IS  - 1976-8257 (Linking)
VI  - 26
IP  - 2
DP  - 2010 Jun
TI  - Determination of Trichlorfon Pesticide Residues in Milk via Gas Chromatography 
      with mu-Electron Capture Detection and GC-MS.
PG  - 149-55
LID - 10.5487/TR.2010.26.2.149 [doi]
AB  - The pesticide trichlorfon is readily degraded under experimental conditions to 
      dichlorvos. A method has therefore been developed by which residues of 
      trichlorfon in milk are determined as dichlorvos, using gas chromatography with 
      mu-electron capture detection. The identification of dichlorvos was confirmed by 
      mass spectrometry. Milk was extracted with acetonitrile followed by 
      centrifugation, freezing lipid filtration, and partitioning into dichloromethane. 
      The residue after partitioning of dichloromethane was dissolved in ethyl acetate 
      for gas chromatography. Recovery concentration was determined at 0.5, 1.0, and 
      2.0 of times the maximum permitted residue limits (MRLs) for trichlorfon in milk. 
      The average recoveries (n = 6) ranged from 92.4 to 103.6%. The repeatability of 
      the measurements was expressed as relative standard deviations (RSDs) ranging 
      from 3.6%, to 6.7%. Limit of detection (LOD) and limit of quantification (LOQ) 
      were 3.7 and 11.1 mug/l, respectively. The accuracy and precision (expressed as 
      RSD) were estimated at concentrations from 25 to 250 mug/l. The intra- and 
      inter-day accuracy (n = 6) ranged from 89.2%to 91% and 91.3% to 96.3%, 
      respectively. The intra- and inter-day precisions were lower than 8%. The 
      developed method was applied to determine trichlorfon in real samples collected 
      from the seven major cities in the Republic of Korea. No residual trichlorfon was 
      detected in any samples.
FAU - Hem, Lina
AU  - Hem L
AD  - Natural Products Chemistry Laboratory, Division of Applied Bioscience and 
      Biotechnology, College of Agriculture and Life Science, Chonnam National 
      University, Gwangju 500-757, Korea.
FAU - Khay, Sathya
AU  - Khay S
FAU - Choi, Jeong-Heui
AU  - Choi JH
FAU - Morgan, E D
AU  - Morgan ED
FAU - Abd El-Aty, A M
AU  - Abd El-Aty AM
FAU - Shim, Jae-Han
AU  - Shim JH
LA  - eng
PT  - Journal Article
PL  - Singapore
TA  - Toxicol Res
JT  - Toxicological research
JID - 101483324
PMC - PMC3834475
OTO - NOTNLM
OT  - Dichlorvos
OT  - Gas chromatography
OT  - Mass spectrometry
OT  - Milk
OT  - Trichlorfon
EDAT- 2010/06/01 00:00
MHDA- 2010/06/01 00:01
PMCR- 2010/07/01
CRDT- 2013/11/27 06:00
PHST- 2010/02/23 00:00 [received]
PHST- 2010/05/22 00:00 [revised]
PHST- 2010/05/24 00:00 [accepted]
PHST- 2013/11/27 06:00 [entrez]
PHST- 2010/06/01 00:00 [pubmed]
PHST- 2010/06/01 00:01 [medline]
PHST- 2010/07/01 00:00 [pmc-release]
AID - toxicr-26-149 [pii]
AID - 10.5487/TR.2010.26.2.149 [doi]
PST - ppublish
SO  - Toxicol Res. 2010 Jun;26(2):149-55. doi: 10.5487/TR.2010.26.2.149.