PMID- 24280468
OWN - NLM
STAT- MEDLINE
DCOM- 20140715
LR  - 20211012
IS  - 1873-6963 (Electronic)
IS  - 0965-2299 (Linking)
VI  - 21
IP  - 6
DP  - 2013 Dec
TI  - Essential hypertension treated by wuling powder and modified tianma gouteng 
      decoction: a cohort study without controls.
PG  - 609-12
LID - S0965-2299(13)00165-9 [pii]
LID - 10.1016/j.ctim.2013.09.007 [doi]
AB  - OBJECTIVE: To evaluate the efficacy and safety of wuling powder and modified 
      tianma gouteng decoction as an open add-on therapy for treating essential 
      hypertension (EH). METHODS: 72 cases of EH patients took wuling powder and 
      modified tianma gouteng decoction for 2 weeks to treat EH without changing their 
      former medication. New York Heart Association (NYHA) heart function 
      classification, heart rate, blood pressure and 6-min walking test were evaluated 
      before and after treatment. RESULTS: Wuling powder and modified tianma gouteng 
      decoction decreased the EH patients' heart rate, systolic pressure, diastolic 
      pressure and increased the 6-min walking distance very significantly (P<0.01). 
      The total effective rate on blood pressure was 91.7%, and the total effective 
      rate on NYHA heart function improvement was 95.1%. No serious side effect 
      appeared. CONCLUSION: From this study, treating EH with wuling powder and 
      modified tianma gouteng decoction as an open add-on therapy seems to be effective 
      and safe. Further randomized trials are needed to test the positive findings.
CI  - Copyright (c) 2013 Elsevier Ltd. All rights reserved.
FAU - Ke, Youfu
AU  - Ke Y
AD  - The University of Hong Kong, School of Chinese Medicine, 999077, Hong Kong, 
      China. Electronic address: keyoufu@gmail.com.
FAU - Pu, Jinbao
AU  - Pu J
FAU - Zheng, Junxian
AU  - Zheng J
LA  - eng
PT  - Journal Article
DEP - 20130925
PL  - Scotland
TA  - Complement Ther Med
JT  - Complementary therapies in medicine
JID - 9308777
RN  - 0 (Drugs, Chinese Herbal)
RN  - 0 (wuling)
RN  - 1XCM98TE9T (gou-teng)
SB  - IM
MH  - Aged
MH  - Cohort Studies
MH  - Drugs, Chinese Herbal/*therapeutic use
MH  - Essential Hypertension
MH  - Female
MH  - Heart Function Tests/drug effects
MH  - Humans
MH  - Hypertension/*drug therapy
MH  - Male
MH  - Middle Aged
MH  - Phytotherapy/methods
OTO - NOTNLM
OT  - Chronic heart failure
OT  - Essential hypertension
OT  - Tianma gouteng decoction
OT  - Wuling powder
EDAT- 2013/11/28 06:00
MHDA- 2014/07/16 06:00
CRDT- 2013/11/28 06:00
PHST- 2012/08/05 00:00 [received]
PHST- 2013/07/24 00:00 [revised]
PHST- 2013/09/15 00:00 [accepted]
PHST- 2013/11/28 06:00 [entrez]
PHST- 2013/11/28 06:00 [pubmed]
PHST- 2014/07/16 06:00 [medline]
AID - S0965-2299(13)00165-9 [pii]
AID - 10.1016/j.ctim.2013.09.007 [doi]
PST - ppublish
SO  - Complement Ther Med. 2013 Dec;21(6):609-12. doi: 10.1016/j.ctim.2013.09.007. Epub 
      2013 Sep 25.