PMID- 24282103
OWN - NLM
STAT- MEDLINE
DCOM- 20141103
LR  - 20220410
IS  - 1552-695X (Electronic)
IS  - 1534-7354 (Linking)
VI  - 13
IP  - 2
DP  - 2014 Mar
TI  - Acupuncture for treatment of uncontrolled pain in cancer patients: a pragmatic 
      pilot study.
PG  - 133-40
LID - 10.1177/1534735413510558 [doi]
AB  - PURPOSE: Pain control is an ongoing challenge in the oncology setting. Prior to 
      implementing a large randomized trial at our institution, we investigated the 
      feasibility, safety, and initial efficacy of acupuncture for uncontrolled pain 
      among cancer patients. HYPOTHESES: Our hypotheses were that the acupuncture 
      treatments provided would be ( : ) feasible, ( : ) safe, and ( : ) a beneficial 
      adjunct to pain management. STUDY DESIGN: This was a single arm, nonrandomized 
      pragmatic pilot study. METHODS: Participants experiencing pain >/=4 on a 0 to 10 
      numeric rating scale received a maximum of 10 treatments on an individualized 
      basis. Recruitment, attrition, compliance, and adverse events (AEs) were 
      assessed. Pain (Brief Pain Inventory-Short Form), quality of life (MD Anderson 
      Symptom Inventory [MDASI]), and patient satisfaction were assessed at baseline 
      and at the end of treatment. RESULTS: Of 115 patients screened, 52 (45%) were 
      eligible and agreed to participate. Eleven (21%) were lost to follow-up, leaving 
      41 who completed all study procedures. No AEs were reported. Mean pain SEVERIT: 
      was 6.0 +/- 1.3 at baseline and 3.8 +/- 2.0 at follow-up ( : < .0001). Pain 
      INTERFERENC: was 6.2 +/- 2.3 at baseline and 4.3 +/- 2.8 at follow-up ( : < .0011). 
      On the MDASI, the mean symptom SEVERIT: was 4.6 +/- 1.8 at baseline and 3.2 +/- 1.9 
      at follow-up ( : < .0001), and mean symptom INTERFERENC: was 5.8 +/- 2.4 at 
      baseline and 4.1 +/- 2.9 at follow-up ( : < .002). Prescribed pain medications 
      decreased across the course of the study. Patient satisfaction was high: 87% 
      reported that their expectations were met "very well" or "extremely well"; 90% 
      said they were likely to participate again; 95% said they were likely to 
      recommend acupuncture to others; and 90% reported they found the service to be 
      "useful" or "very useful." CONCLUSIONS: Acupuncture was feasible, safe, and a 
      helpful treatment adjunct for cancer patients experiencing uncontrolled pain in 
      this study. Randomized placebo-controlled trials are needed to confirm these 
      results.
FAU - Garcia, M Kay
AU  - Garcia MK
AD  - The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
FAU - Driver, Larry
AU  - Driver L
FAU - Haddad, Robin
AU  - Haddad R
FAU - Lee, Richard
AU  - Lee R
FAU - Palmer, J Lynn
AU  - Palmer JL
FAU - Wei, Qi
AU  - Wei Q
FAU - Frenkel, Moshe
AU  - Frenkel M
FAU - Cohen, Lorenzo
AU  - Cohen L
LA  - eng
GR  - CA016672/CA/NCI NIH HHS/United States
GR  - CA121503/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20131125
PL  - United States
TA  - Integr Cancer Ther
JT  - Integrative cancer therapies
JID - 101128834
SB  - IM
MH  - Acupuncture Therapy/*methods
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neoplasms/*complications
MH  - Pain/*physiopathology
MH  - Pain Management/*methods
MH  - Pilot Projects
OTO - NOTNLM
OT  - acupuncture
OT  - cancer
OT  - complementary medicine
OT  - integrative medicine
OT  - pain
OT  - symptom management
EDAT- 2013/11/28 06:00
MHDA- 2014/11/05 06:00
CRDT- 2013/11/28 06:00
PHST- 2013/11/28 06:00 [entrez]
PHST- 2013/11/28 06:00 [pubmed]
PHST- 2014/11/05 06:00 [medline]
AID - 1534735413510558 [pii]
AID - 10.1177/1534735413510558 [doi]
PST - ppublish
SO  - Integr Cancer Ther. 2014 Mar;13(2):133-40. doi: 10.1177/1534735413510558. Epub 
      2013 Nov 25.