PMID- 24290429
OWN - NLM
STAT- MEDLINE
DCOM- 20140519
LR  - 20181202
IS  - 1095-8673 (Electronic)
IS  - 0022-4804 (Linking)
VI  - 187
IP  - 2
DP  - 2014 Apr
TI  - Radiofrequency-assisted versus clamp-crush liver resection: a systematic review 
      and meta-analysis.
PG  - 471-83
LID - S0022-4804(13)00995-5 [pii]
LID - 10.1016/j.jss.2013.10.055 [doi]
AB  - BACKGROUND: Conflicting results were found between radiofrequency-assisted liver 
      resection (RF-LR) and clamp-crush liver resection (CC-LR) during liver surgery. 
      We conducted a systematic review and meta-analysis that included randomized 
      controlled trials (RCTs) and non-RCTs to compare the effectiveness and safety of 
      RF-LR versus CC-LR during liver surgery. METHODS: Articles comparing RF-LR and 
      CC-LR that were published before December 2012 were retrieved and subjected to a 
      systematic review and meta-analysis. Data synthesis and statistical analysis were 
      carried out by Review Manager Version 5.2 software. RESULTS: In all, four RCTs 
      and five nonrandomized studies evaluating 728 patients were included. Compared 
      with CC-LR, the RF-LR group had significantly reduced total intraoperative blood 
      loss (weighted mean difference [WMD] = -187 mL; 95% confidence interval 
      [CI] = -312, -62; data on 628 patients), and blood loss during liver transection 
      (WMD = -143.7 mL; 95% CI = -200, -87; data on 190 patients). However, RF-LR is 
      associated with a higher rate of intra-abdominal abscess than the clamp-crushing 
      method (odds ratio = 3.61; 95% CI = 1.26, 10.32; data on 366 patients). No 
      significant difference was observed between both the groups for the incidence of 
      both blood transfusion and bile leak. CONCLUSIONS: There is currently not 
      sufficient evidence to support or refute the use of RF-LR in liver surgery. RF-LR 
      has advantages in terms of reducing blood loss. However, RF-LR may increase the 
      rates of both bile leak and abdominal abscess. So, the safety of RF-LR has not 
      been established. Future well-designed RCTs are awaited to further investigate 
      the efficacy and safety of RF devices in liver resection.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Xiao, Wei-Kai
AU  - Xiao WK
AD  - Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen 
      University, Guangzhou, China.
FAU - Chen, Dong
AU  - Chen D
AD  - Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen 
      University, Guangzhou, China.
FAU - Hu, An-Bin
AU  - Hu AB
AD  - Department of General Surgery, The First Affiliated Hospital, Sun Yat-sen 
      University, Guangzhou, China.
FAU - Peng, Bao-Gang
AU  - Peng BG
AD  - Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen 
      University, Guangzhou, China.
FAU - Guo, Yi-Zhan
AU  - Guo YZ
AD  - Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen 
      University, Guangzhou, China.
FAU - Fu, Shun-Jun
AU  - Fu SJ
AD  - Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen 
      University, Guangzhou, China.
FAU - Liang, Li-Jian
AU  - Liang LJ
AD  - Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen 
      University, Guangzhou, China.
FAU - Li, Shao-Qiang
AU  - Li SQ
AD  - Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen 
      University, Guangzhou, China. Electronic address: lisq@medmail.com.cn.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20131031
PL  - United States
TA  - J Surg Res
JT  - The Journal of surgical research
JID - 0376340
SB  - IM
MH  - Catheter Ablation/*methods
MH  - Hemostasis, Surgical/*methods
MH  - Hepatectomy/instrumentation/*methods
MH  - Humans
MH  - Liver Diseases/*surgery
MH  - Liver Neoplasms/*surgery
MH  - Randomized Controlled Trials as Topic
MH  - Surgical Instruments
OTO - NOTNLM
OT  - Clamp-crush liver resection
OT  - Meta-analysis
OT  - Radiofrequency-assisted liver resection
OT  - Systematic review
EDAT- 2013/12/03 06:00
MHDA- 2014/05/20 06:00
CRDT- 2013/12/03 06:00
PHST- 2013/08/30 00:00 [received]
PHST- 2013/10/21 00:00 [revised]
PHST- 2013/10/25 00:00 [accepted]
PHST- 2013/12/03 06:00 [entrez]
PHST- 2013/12/03 06:00 [pubmed]
PHST- 2014/05/20 06:00 [medline]
AID - S0022-4804(13)00995-5 [pii]
AID - 10.1016/j.jss.2013.10.055 [doi]
PST - ppublish
SO  - J Surg Res. 2014 Apr;187(2):471-83. doi: 10.1016/j.jss.2013.10.055. Epub 2013 Oct 
      31.