PMID- 24293405
OWN - NLM
STAT- MEDLINE
DCOM- 20150701
LR  - 20161125
IS  - 1522-2586 (Electronic)
IS  - 1053-1807 (Linking)
VI  - 40
IP  - 6
DP  - 2014 Dec
TI  - Potentially simple score of late gadolinium enhancement cardiac MR in acute 
      myocarditis outcome.
PG  - 1347-54
LID - 10.1002/jmri.24504 [doi]
AB  - PURPOSE: To determine the value of cardiac MRI for the monitoring and the 
      prognosis of patients with acute myocarditis. Cardiac MRI plays an increasingly 
      important role in the diagnosis of acute myocarditis. However, it is less 
      established as a prognostic tool, which requires specific postprocessing of 
      images. MATERIALS AND METHODS: In a prospective pilot study, we assessed the 
      prognostic value of the evolution in a simplified visual quantitative score (SQS) 
      of late gadolinium enhancement (LGE) between initial hospitalization and 3 months 
      later. The prognostic value was assessed at 1 year using a combination of death, 
      heart transplant, and confirmed recurrence as main outcome. RESULTS: Twenty-eight 
      patients were included in this study. A significant correlation was found between 
      LGE measured by SQS and planimetry (r = 0.95, P < 0.001). Intraobserver and 
      interobserver reproducibilities were good for SQS (ICC = 0.95 [95% CI: 0.86 to 
      0.98], and 0.94 [95% CI: 0.84 to 0.98], respectively). At initial 
      hospitalization, patient characteristics between the two groups were similar. 
      Patients with stable or increased SQS suffered more frequently from clinical 
      outcome events than patients with a decrease in SQS (P = 0.02). CONCLUSION: 
      Monitoring of the evolution of LGE using a simple visual score is of interest to 
      identify patients at risk of pejorative prognosis after acute myocarditis.
CI  - (c) 2013 Wiley Periodicals, Inc.
FAU - Barone-Rochette, Gilles
AU  - Barone-Rochette G
AD  - Department of Cardiology, University Hospital, Grenoble, France; INSERM U 1039, 
      Bioclinic Radiopharmaceutics Laboratory, Grenoble, France.
FAU - Augier, Caroline
AU  - Augier C
FAU - Rodiere, Mathieu
AU  - Rodiere M
FAU - Quesada, Jean-Louis
AU  - Quesada JL
FAU - Foote, Alison
AU  - Foote A
FAU - Bouvaist, Helene
AU  - Bouvaist H
FAU - Marliere, Stephanie
AU  - Marliere S
FAU - Fagret, Daniel
AU  - Fagret D
FAU - Baguet, Jean Philippe
AU  - Baguet JP
FAU - Vanzetto, Gerald
AU  - Vanzetto G
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20131201
PL  - United States
TA  - J Magn Reson Imaging
JT  - Journal of magnetic resonance imaging : JMRI
JID - 9105850
RN  - 0 (Contrast Media)
RN  - 0 (Organometallic Compounds)
RN  - 6HG8UB2MUY (Meglumine)
RN  - L0ND3981AG (gadoterate meglumine)
SB  - IM
MH  - Acute Disease
MH  - *Algorithms
MH  - Contrast Media
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Image Enhancement/methods
MH  - Image Interpretation, Computer-Assisted/*methods
MH  - Magnetic Resonance Imaging, Cine/*methods
MH  - Male
MH  - *Meglumine
MH  - Myocarditis/*pathology/*therapy
MH  - *Organometallic Compounds
MH  - Prognosis
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Treatment Outcome
OTO - NOTNLM
OT  - cardiac magnetic resonance
OT  - delayed gadolinium-enhancement
OT  - myocarditis
OT  - prognosis
EDAT- 2013/12/03 06:00
MHDA- 2015/07/02 06:00
CRDT- 2013/12/03 06:00
PHST- 2013/04/21 00:00 [received]
PHST- 2013/10/14 00:00 [accepted]
PHST- 2013/12/03 06:00 [entrez]
PHST- 2013/12/03 06:00 [pubmed]
PHST- 2015/07/02 06:00 [medline]
AID - 10.1002/jmri.24504 [doi]
PST - ppublish
SO  - J Magn Reson Imaging. 2014 Dec;40(6):1347-54. doi: 10.1002/jmri.24504. Epub 2013 
      Dec 1.