PMID- 24294188
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20131202
LR  - 20211021
IS  - 1318-2099 (Print)
IS  - 1581-3207 (Electronic)
IS  - 1318-2099 (Linking)
VI  - 47
IP  - 4
DP  - 2013
TI  - Dosimetric evaluation of an ipsilateral intensity modulated radiotherapy beam 
      arrangement for parotid malignancies.
PG  - 411-8
LID - 10.2478/raon-2013-0010 [doi]
AB  - BACKGROUND: We conducted a dosimetric comparison of an ipsilateral beam 
      arrangement for intensity modulated radiotherapy (IMRT) with off-axis beams. 
      PATIENTS AND METHODS: Six patients who received post-operative radiotherapy (RT) 
      for parotid malignancies were used in this dosimetric study. Four treatment plans 
      were created for each CT data set (24 plans): 1) ipsilateral 4-field off-axis 
      IMRT (4fld-OA), 2) conventional wedge pair (WP), 3) 7 field co-planar IMRT 
      (7fld), and 4) ipsilateral co-planar 4-field quartet IMRT (4fld-CP). Dose, volume 
      statistics for the planning target volumes (PTVs) and planning risk volumes 
      (PRVs) were compared for the four treatment techniques. RESULTS: Wedge pair plans 
      inadequately covered the deep aspect of the PTV. The 7-field IMRT plans delivered 
      the largest low dose volumes to normal tissues. Mean dose to the contralateral 
      parotid was highest for 7 field IMRT. Mean dose to the contralateral 
      submandibular gland was highest for 7 field IMRT and WP. 7 field IMRT plans had 
      the highest dose to the oral cavity. The mean doses to the brainstem, spinal 
      cord, ipsilateral temporal lobe, cerrebellum and ipsilateral cochlea were similar 
      among the four techniques. CONCLUSIONS: For postoperative treatment of the 
      parotid bed, 4-field ipsilateral IMRT techniques provided excellent coverage 
      while maximally sparing the contralateral parotid gland and submandibular gland.
FAU - Yirmibesoglu, Eda
AU  - Yirmibesoglu E
AD  - Department of Radiation Oncology, Kocaeli University Faculty of Medicine, 
      Kocaeli, Turkey ; Department of Radiation Oncology, University of North Carolina 
      Hospitals, Chapel Hill, NC, USA.
FAU - Fried, David V
AU  - Fried DV
FAU - Kostich, Mark
AU  - Kostich M
FAU - Rosenman, Julian
AU  - Rosenman J
FAU - Shockley, William
AU  - Shockley W
FAU - Weissler, Mark
AU  - Weissler M
FAU - Zanation, Adam
AU  - Zanation A
FAU - Chera, Bhishamjit
AU  - Chera B
LA  - eng
PT  - Journal Article
DEP - 20131008
PL  - Poland
TA  - Radiol Oncol
JT  - Radiology and oncology
JID - 9317213
PMC - PMC3814288
OTO - NOTNLM
OT  - dosimetry
OT  - intensity modulated radiotherapy
OT  - parotid
EDAT- 2013/12/03 06:00
MHDA- 2013/12/03 06:01
PMCR- 2013/12/01
CRDT- 2013/12/03 06:00
PHST- 2012/08/27 00:00 [received]
PHST- 2012/11/25 00:00 [accepted]
PHST- 2013/12/03 06:00 [entrez]
PHST- 2013/12/03 06:00 [pubmed]
PHST- 2013/12/03 06:01 [medline]
PHST- 2013/12/01 00:00 [pmc-release]
AID - rado-47-04-411 [pii]
AID - 10.2478/raon-2013-0010 [doi]
PST - epublish
SO  - Radiol Oncol. 2013 Oct 8;47(4):411-8. doi: 10.2478/raon-2013-0010. eCollection 
      2013.