PMID- 24304492
OWN - NLM
STAT- MEDLINE
DCOM- 20141103
LR  - 20220311
IS  - 1502-7686 (Electronic)
IS  - 0036-5513 (Linking)
VI  - 74
IP  - 2
DP  - 2014 Mar
TI  - The relationship between high-sensitive troponin T, neutrophil lymphocyte ratio 
      and SYNTAX Score.
PG  - 108-15
LID - 10.3109/00365513.2013.860619 [doi]
AB  - AIM: Cardiac troponins are the most preferred biomarkers in the evaluation of 
      acute coronary syndromes (ACS). The aim of our study was to examine the 
      association between high sensitive troponin T (hs-TnT), and neutrophil to 
      lymphocyte ratio (NLR) and the complexity of ACS assessed by SYNTAX Score. 
      METHODS AND RESULTS: 287 patients who underwent coronary angiography were studied 
      (215 male, mean age 62.0 +/- 12.7 years). 133 patients were ST elevation myocardial 
      infarction (STEMI), 154 patients were non-ST elevation (NSTE) ACS . The patients 
      are divided to tertiles according to SYNTAX Score; SYNTAX Score </= 22 (n = 122) 22 
      < SYNTAX Score </= 32 (n = 120), and SYNTAX Score > 32 (n = 45). NLR was 
      significantly correlated with SYNTAX Score in both STEMI and NSTE-ACS groups (r = 
      0.254, p = 0.003, r = 0.419 p < 0.001). Multiple linear regression analysis 
      showed NLR predicted the angiographic severity of ACS assessed by SYNTAX Score in 
      two groups (beta = 0.231, p = 0.004; beta = 0.232, p = 0.003). Hs-TnT was significantly 
      correlated with SYNTAX Score in two groups (r = 0.327, p < 0.001; r = 0.430, p < 
      0.001). Multiple linear regression analysis showed hs-TnT was independent 
      predictor of SYNTAX Score in STEMI and NSTE-ACS patients (beta = 0.292, p < 0.001; beta 
      = 0.317, p < 0.001). CONCLUSION: Hs-TnT and NLR were significantly correlated 
      with angiographic severity of ACS assessed by SYNTAX Score.
FAU - Altun, Burak
AU  - Altun B
AD  - Department of Cardiology.
FAU - Turkon, Hakan
AU  - Turkon H
FAU - Tasolar, Hakan
AU  - Tasolar H
FAU - Beggi, Halil
AU  - Beggi H
FAU - Altun, Mehzat
AU  - Altun M
FAU - Temiz, Ahmet
AU  - Temiz A
FAU - Gazi, Emine
AU  - Gazi E
FAU - Barutcu, Ahmet
AU  - Barutcu A
FAU - Bekler, Adem
AU  - Bekler A
FAU - Colkesen, Yucel
AU  - Colkesen Y
LA  - eng
PT  - Journal Article
DEP - 20131205
PL  - England
TA  - Scand J Clin Lab Invest
JT  - Scandinavian journal of clinical and laboratory investigation
JID - 0404375
RN  - 0 (Biomarkers)
RN  - 0 (Troponin T)
SB  - IM
MH  - Acute Coronary Syndrome/blood/*diagnosis/diagnostic imaging/pathology
MH  - Aged
MH  - Biomarkers/blood
MH  - Coronary Angiography
MH  - Female
MH  - Humans
MH  - Leukocyte Count
MH  - Lymphocytes/pathology
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/blood/*diagnosis/diagnostic imaging/pathology
MH  - Neutrophils/pathology
MH  - Retrospective Studies
MH  - *Severity of Illness Index
MH  - Troponin T/blood
EDAT- 2013/12/07 06:00
MHDA- 2014/11/05 06:00
CRDT- 2013/12/06 06:00
PHST- 2013/12/06 06:00 [entrez]
PHST- 2013/12/07 06:00 [pubmed]
PHST- 2014/11/05 06:00 [medline]
AID - 10.3109/00365513.2013.860619 [doi]
PST - ppublish
SO  - Scand J Clin Lab Invest. 2014 Mar;74(2):108-15. doi: 
      10.3109/00365513.2013.860619. Epub 2013 Dec 5.