PMID- 24304604
OWN - NLM
STAT- MEDLINE
DCOM- 20141215
LR  - 20211021
IS  - 1559-2324 (Electronic)
IS  - 1559-2316 (Print)
IS  - 1559-2316 (Linking)
VI  - 8
IP  - 11
DP  - 2013 Nov
TI  - Organization of protein complexes under photomorphogenic UV-B in Arabidopsis.
PG  - e27206
LID - 10.4161/psb.27206 [doi]
LID - e27206
AB  - Low-fluence and long-wavelength UV-B (UV-B) light promotes photomorphogenic 
      development in Arabidopsis. CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) is a positive 
      regulator in this pathway while it is a negative regulator of the traditional 
      photomorphogenesis triggered by far-red and visible light. We have recently 
      reported the mechanism by which the switch of COP1 function is accomplished in 
      distinct light contexts. In response to photomorphogenic UV-B, the photoactivated 
      UV RESISTANCE LOCUS 8 (UVR8) associates with the COP1- SUPRESSOR OF PHYA (SPA) 
      core complexes, resulting in the physical and functional disassociation of 
      COP1-SPA from the CULLIN4-DAMAGED DNA BINDING PROTEIN 1 (CUL4-DDB1) E3 scaffold. 
      These UV-B dependent UVR8-COP1-SPA complexes promote the stability and activity 
      of ELONGATED HYPOCOTYL 5 (HY5), and eventually cause COP1 to switch from 
      repressing to promoting photomorphogenesis. In addition, it is possible that 
      CUL4-DDB1 might simultaneously recruit alternative DDB1 BINDING WD40 (DWD) 
      proteins to repress this UV-B-specific signaling. Further investigation is 
      required, however, to verify this hypothesis. Overall, the coordinated 
      organization of various protein complexes facilitates an efficient and balanced 
      UV-B signaling.
FAU - Huang, Xi
AU  - Huang X
AD  - Peking-Yale Joint Center for Plant Molecular Genetics and Agro-Biotechnology; 
      National Laboratory of Protein Engineering and Plant Genetic Engineering; College 
      of Life Sciences; Peking University; Beijing, PR China.
FAU - Deng, Xing Wang
AU  - Deng XW
AD  - Peking-Yale Joint Center for Plant Molecular Genetics and Agro-Biotechnology; 
      National Laboratory of Protein Engineering and Plant Genetic Engineering; College 
      of Life Sciences; Peking University; Beijing, PR China.
LA  - eng
PT  - Journal Article
DEP - 20131204
PL  - United States
TA  - Plant Signal Behav
JT  - Plant signaling & behavior
JID - 101291431
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (Multiprotein Complexes)
SB  - IM
MH  - Arabidopsis/*growth & development/metabolism/*radiation effects
MH  - Arabidopsis Proteins/*metabolism
MH  - Models, Biological
MH  - Morphogenesis/*radiation effects
MH  - Multiprotein Complexes/*metabolism
MH  - Signal Transduction/radiation effects
MH  - *Ultraviolet Rays
PMC - PMC4091229
OTO - NOTNLM
OT  - UV-B
OT  - light signaling
OT  - protein complex
EDAT- 2013/12/07 06:00
MHDA- 2014/12/17 06:00
PMCR- 2014/06/04
CRDT- 2013/12/06 06:00
PHST- 2013/12/06 06:00 [entrez]
PHST- 2013/12/07 06:00 [pubmed]
PHST- 2014/12/17 06:00 [medline]
PHST- 2014/06/04 00:00 [pmc-release]
AID - 27206 [pii]
AID - 2013PSB0399 [pii]
AID - 10.4161/psb.27206 [doi]
PST - ppublish
SO  - Plant Signal Behav. 2013 Nov;8(11):e27206. doi: 10.4161/psb.27206. Epub 2013 Dec 
      4.