PMID- 24305633
OWN - NLM
STAT- MEDLINE
DCOM- 20150212
LR  - 20211118
IS  - 1347-4820 (Electronic)
IS  - 1346-9843 (Linking)
VI  - 78
IP  - 2
DP  - 2014
TI  - Differences in negative T waves between acute pulmonary embolism and acute 
      coronary syndrome.
PG  - 483-9
AB  - BACKGROUND: Patients with acute pulmonary embolism (APE) often have negative T 
      waves (Neg T) in precordial leads at presentation, but this is also found in 
      acute coronary syndrome (ACS) caused by left anterior descending coronary artery 
      (LAD) disease. METHODS AND RESULTS: Differences in Neg T on admission 
      electrocardiograms were studied between 107 patients with APE and 248 patients 
      with ACS caused by LAD disease. All patients had Neg T in leads V1-4 and were 
      admitted within 7 days from symptom onset. The number of leads with Neg T 
      (4.8+/-1.8 vs. 5.5+/-1.7, P<0.001) and maximum magnitude of Neg T (3.4+/-2.0 vs. 
      4.7+/-3.3mm, P<0.001) were lower in APE. The frequency of occurrence of Neg T in 
      each of the 12 leads, and the precordial lead with the greatest Neg T (peak Neg 
      T) differed between APE and ACS (all P<0.05, respectively). APE was strongly 
      associated with the presence of Neg T in both leads III and V1 and peak Neg T in 
      leads V1-2. The combination of these 2 findings identified APE with 98% 
      sensitivity, 92% specificity, and 94% predictive accuracy, which represented the 
      highest diagnostic accuracy. CONCLUSIONS: Among patients with APE and ACS who 
      have precordial Neg T, the presence of Neg T in leads III and V1 and/or peak Neg 
      T in leads V1-2 simply but accurately differentiates APE from ACS.  
FAU - Kosuge, Masami
AU  - Kosuge M
AD  - Division of Cardiology, Yokohama City University Medical Center.
FAU - Ebina, Toshiaki
AU  - Ebina T
FAU - Hibi, Kiyoshi
AU  - Hibi K
FAU - Tsukahara, Kengo
AU  - Tsukahara K
FAU - Iwahashi, Noriaki
AU  - Iwahashi N
FAU - Umemura, Satoshi
AU  - Umemura S
FAU - Kimura, Kazuo
AU  - Kimura K
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
DEP - 20131203
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
SB  - IM
CIN - Circ J. 2021 Jul 21;85(8):1405. PMID: 34135262
CIN - Circ J. 2021 Jul 21;85(8):1406. PMID: 34135263
MH  - Acute Coronary Syndrome/*physiopathology
MH  - Aged
MH  - *Electrocardiography
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pulmonary Embolism/*physiopathology
MH  - Retrospective Studies
EDAT- 2013/12/07 06:00
MHDA- 2015/02/13 06:00
CRDT- 2013/12/06 06:00
PHST- 2013/12/06 06:00 [entrez]
PHST- 2013/12/07 06:00 [pubmed]
PHST- 2015/02/13 06:00 [medline]
AID - DN/JST.JSTAGE/circj/CJ-13-1064 [pii]
AID - 10.1253/circj.cj-13-1064 [doi]
PST - ppublish
SO  - Circ J. 2014;78(2):483-9. doi: 10.1253/circj.cj-13-1064. Epub 2013 Dec 3.