PMID- 24306157
OWN - NLM
STAT- MEDLINE
DCOM- 20140728
LR  - 20131205
IS  - 1871-403X (Print)
IS  - 1871-403X (Linking)
VI  - 7
IP  - 4
DP  - 2013 Jul-Aug
TI  - 2 years change of waist circumference and body mass index and associations with 
      type 2 diabetes mellitus in cohort populations.
PG  - e290-6
LID - S1871-403X(12)00014-2 [pii]
LID - 10.1016/j.orcp.2012.02.005 [doi]
AB  - OBJECTIVE: Compare the association between 2 years change of waist circumference 
      (WC) or body mass index (BMI) and incident type 2 diabetes mellitus (T2DM) in 
      cohort populations. METHODS: Prospective cohort study, based on a baseline 
      investigation from 1999, we conducted the first follow-up for subjects whose 
      follow time met 2 years, and the second follow-up for subjects whose follow time 
      met 5 years. Two years change of WC or BMI was measured by the D-value between 
      baseline and the first follow up values. The association between 2 years change 
      of WC or BMI and incident T2DM were analyzed by using Poisson regression model. 
      RESULTS: Among 3461 participants without T2DM at baseline, 160 subjects developed 
      T2DM during follow up period. Across quartiles of WC D-value, hazards ratio (HR) 
      of incident T2DM increased, but there was no significant dose response 
      relationship was found between BMI D-value and incident T2DM. Compared with 
      subjects whose both WC and BMI were modified, there was no significant increase 
      for T2DM risk in subjects whose WC was modified but BMI was not modified 
      [HR(95%CI) = 1.66(0.70-3.97)], but the T2DM risk was significantly higher in 
      subjects whose WC was not modified but BMI was modified [HR(95%CI) = 
      1.73(1.17-2.54)]. CONCLUSIONS: WC change was a better predictor for incident T2DM 
      than BMI change. Intervention programs designed to reduce WC through lifestyle 
      modification, including physical activity and diet, may have significant public 
      health significance in preventing incident T2DM.
CI  - A(c) 2013 Asian Oceanian Association for the Study of Obesity . Published by 
      Elsevier Ltd. All rights reserved.
FAU - Luo, Wenshu
AU  - Luo W
AD  - Department of Radiology & Public Health, Soochow University, SuZhou, JiangSu 
      215123, China.
FAU - Guo, Zhirong
AU  - Guo Z
FAU - Hu, Xiaoshu
AU  - Hu X
FAU - Zhou, Zhengyuan
AU  - Zhou Z
FAU - Wu, Ming
AU  - Wu M
FAU - Zhang, Lijun
AU  - Zhang L
FAU - Liu, Jingchao
AU  - Liu J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Obes Res Clin Pract
JT  - Obesity research & clinical practice
JID - 101303911
SB  - IM
MH  - Adult
MH  - *Body Mass Index
MH  - China/epidemiology
MH  - Diabetes Mellitus, Type 2/*epidemiology
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Obesity/epidemiology
MH  - Prospective Studies
MH  - Regression Analysis
MH  - Risk Factors
MH  - *Waist Circumference
EDAT- 2013/12/07 06:00
MHDA- 2014/07/30 06:00
CRDT- 2013/12/06 06:00
PHST- 2011/09/04 00:00 [received]
PHST- 2012/02/05 00:00 [revised]
PHST- 2012/02/08 00:00 [accepted]
PHST- 2013/12/06 06:00 [entrez]
PHST- 2013/12/07 06:00 [pubmed]
PHST- 2014/07/30 06:00 [medline]
AID - S1871-403X(12)00014-2 [pii]
AID - 10.1016/j.orcp.2012.02.005 [doi]
PST - ppublish
SO  - Obes Res Clin Pract. 2013 Jul-Aug;7(4):e290-6. doi: 10.1016/j.orcp.2012.02.005.