PMID- 24319125
OWN - NLM
STAT- MEDLINE
DCOM- 20140403
LR  - 20211021
IS  - 0250-832X (Print)
IS  - 1476-542X (Electronic)
IS  - 0250-832X (Linking)
VI  - 43
IP  - 2
DP  - 2014
TI  - New software for cervical vertebral geometry assessment and its relationship to 
      skeletal maturation--a pilot study.
PG  - 20130238
LID - 10.1259/dmfr.20130238 [doi]
LID - 20130238
AB  - OBJECTIVES: In the present study, we developed new software for quantitative 
      analysis of cervical vertebrae maturation, and we evaluated its applicability 
      through a multinomial logistic regression model (MLRM). METHODS: Digitized images 
      of the bodies of the second (C2), third (C3) and fourth (C4) cervical vertebrae 
      were analysed in cephalometric radiographs of 236 subjects (116 boys and 120 
      girls) by using a software developed for digitized vertebrae analysis. The sample 
      was initially distributed into 11 categories according to the Fishman's skeletal 
      maturity indicators and were then grouped into four stages for quantitative 
      cervical maturational changes (QCMC) analysis (QCMC I, II, III and IV). Seven 
      variables of interest were measured and analysed to identify morphologic 
      alterations of the vertebral bodies in each QCMC category. RESULTS: Statistically 
      significant differences (p < 0.05) were observed among all QCMC categories for 
      the variables analysed. The MLRM used to calculate the probability that an 
      individual belonged to each of the four cervical vertebrae maturation categories 
      was constructed by taking into account gender, chronological age and four 
      variables determined by digitized vertebrae analysis (Ang_C3, MP_C3, MP_C4 and 
      SP_C4). The MLRM presented a predictability of 81.4%. The weighted kappa test showed 
      almost perfect agreement (kappa = 0.832) between the categories defined initially by 
      the method of Fishman and those allocated by the MLRM. CONCLUSIONS: Significant 
      alterations in the morphologies of the C2, C3 and C4 vertebral bodies that were 
      analysed through the digitized vertebrae analysis software occur during the 
      different stages of skeletal maturation. The model that combines the four 
      parameters measured on the vertebral bodies, the age and the gender showed an 
      excellent prediction.
FAU - Santiago, R C
AU  - Santiago RC
AD  - Department of Pediatric Dentistry and Orthodontics, Federal University of Rio de 
      Janeiro, Rio de Janeiro, Brazil.
FAU - Cunha, A R
AU  - Cunha AR
FAU - Junior, G C
AU  - Junior GC
FAU - Fernandes, N
AU  - Fernandes N
FAU - Campos, M J S
AU  - Campos MJ
FAU - Costa, L F M
AU  - Costa LF
FAU - Vitral, R W F
AU  - Vitral RW
FAU - Bolognese, A M
AU  - Bolognese AM
LA  - eng
PT  - Journal Article
DEP - 20131206
PL  - England
TA  - Dentomaxillofac Radiol
JT  - Dento maxillo facial radiology
JID - 7609576
MH  - Age Determination by Skeleton/*methods/statistics & numerical data
MH  - Age Factors
MH  - Aging/physiology
MH  - Carpal Bones/diagnostic imaging
MH  - Cephalometry/methods
MH  - Cervical Vertebrae/diagnostic imaging/*growth & development
MH  - Child
MH  - Cross-Sectional Studies
MH  - Female
MH  - Forecasting
MH  - Hand Bones/diagnostic imaging
MH  - Humans
MH  - Image Processing, Computer-Assisted/methods
MH  - Logistic Models
MH  - Male
MH  - Pilot Projects
MH  - Radiography, Dental, Digital/methods
MH  - Sex Factors
MH  - *Software
PMC - PMC4064620
OTO - NOTNLM
OT  - cervical vertebrae
OT  - logistic regression
OT  - skeletal maturity
EDAT- 2013/12/10 06:00
MHDA- 2014/04/04 06:00
PMCR- 2015/02/01
CRDT- 2013/12/10 06:00
PHST- 2013/12/10 06:00 [entrez]
PHST- 2013/12/10 06:00 [pubmed]
PHST- 2014/04/04 06:00 [medline]
PHST- 2015/02/01 00:00 [pmc-release]
AID - dmfr.20130238 [pii]
AID - 10.1259/dmfr.20130238 [doi]
PST - ppublish
SO  - Dentomaxillofac Radiol. 2014;43(2):20130238. doi: 10.1259/dmfr.20130238. Epub 
      2013 Dec 6.