PMID- 24321407
OWN - NLM
STAT- MEDLINE
DCOM- 20140928
LR  - 20140113
IS  - 1872-7972 (Electronic)
IS  - 0304-3940 (Linking)
VI  - 559
DP  - 2014 Jan 24
TI  - BDNF in quinolinic acid lesioned rats after bone marrow cells transplant.
PG  - 147-51
LID - S0304-3940(13)01071-9 [pii]
LID - 10.1016/j.neulet.2013.11.060 [doi]
AB  - Brain-derived neurotrophic factor (BDNF) concentration was measured in the 
      striatum and cortex after quinolinic acid intrastriatal lesion and 
      transplantation of bone marrow cells (BMSC). The results showed a significant 
      increase of the BDNF levels in the striatum and cortex of the lesioned animals 
      and the ability of the transplanted cells to increase the levels of BDNF in both 
      sites. This recovery of BDNF production and distribution might have beneficial 
      effects and ameliorate the negative consequences of the striatal lesion, a 
      mechanism of potential interest for the treatment of Huntington's disease (HD).
CI  - Copyright (c) 2013 Elsevier Ireland Ltd. All rights reserved.
FAU - Serrano Sanchez, T
AU  - Serrano Sanchez T
AD  - International Center for Neurological Restauration (CIREN), Ave 25 # 15805 entre 
      158 y 160, Cubanacan, Playa, La Habana, Cuba.
FAU - Alberti Amador, E
AU  - Alberti Amador E
AD  - International Center for Neurological Restauration (CIREN), Ave 25 # 15805 entre 
      158 y 160, Cubanacan, Playa, La Habana, Cuba.
FAU - Lorigados Pedre, L
AU  - Lorigados Pedre L
AD  - International Center for Neurological Restauration (CIREN), Ave 25 # 15805 entre 
      158 y 160, Cubanacan, Playa, La Habana, Cuba.
FAU - Blanco Lezcano, L
AU  - Blanco Lezcano L
AD  - International Center for Neurological Restauration (CIREN), Ave 25 # 15805 entre 
      158 y 160, Cubanacan, Playa, La Habana, Cuba.
FAU - Diaz Armesto, I
AU  - Diaz Armesto I
AD  - International Center for Neurological Restauration (CIREN), Ave 25 # 15805 entre 
      158 y 160, Cubanacan, Playa, La Habana, Cuba.
FAU - Bergado, J A
AU  - Bergado JA
AD  - International Center for Neurological Restauration (CIREN), Ave 25 # 15805 entre 
      158 y 160, Cubanacan, Playa, La Habana, Cuba. Electronic address: 
      bergado@neuro.ciren.cu.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20131207
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - F6F0HK1URN (Quinolinic Acid)
SB  - IM
MH  - Animals
MH  - Bone Marrow Transplantation/*methods
MH  - Brain-Derived Neurotrophic Factor/*biosynthesis
MH  - Cerebral Cortex/drug effects/metabolism/surgery
MH  - Corpus Striatum/drug effects/metabolism/surgery
MH  - Male
MH  - Quinolinic Acid/*toxicity
MH  - Rats
MH  - Rats, Sprague-Dawley
OTO - NOTNLM
OT  - Bone marrow stem cells (BMC)
OT  - Brain-derived neurotrophic factor (BDNF)
OT  - Huntington's disease (HD)
OT  - Quinolinic acid
OT  - Transplant
EDAT- 2013/12/11 06:00
MHDA- 2014/10/01 06:00
CRDT- 2013/12/11 06:00
PHST- 2013/09/21 00:00 [received]
PHST- 2013/11/26 00:00 [revised]
PHST- 2013/11/29 00:00 [accepted]
PHST- 2013/12/11 06:00 [entrez]
PHST- 2013/12/11 06:00 [pubmed]
PHST- 2014/10/01 06:00 [medline]
AID - S0304-3940(13)01071-9 [pii]
AID - 10.1016/j.neulet.2013.11.060 [doi]
PST - ppublish
SO  - Neurosci Lett. 2014 Jan 24;559:147-51. doi: 10.1016/j.neulet.2013.11.060. Epub 
      2013 Dec 7.