PMID- 24326131
OWN - NLM
STAT- MEDLINE
DCOM- 20140822
LR  - 20181202
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1324
DP  - 2014 Jan 10
TI  - Determination of 23 phthalic acid esters in food by liquid chromatography tandem 
      mass spectrometry.
PG  - 49-56
LID - S0021-9673(13)01788-3 [pii]
LID - 10.1016/j.chroma.2013.11.017 [doi]
AB  - A rapid and sensitive method was developed for the determination of 23 phthalates 
      in food samples including milk-based products, distilled liquor, wine, beverage, 
      grain, meat, oil, biscuit (cookie), and canned food by liquid chromatography 
      tandem mass spectrometry (LC-MS/MS). Liquid samples were exacted by acetonitrile, 
      while solid samples were prepared by QuEChERS or glass-based SPE methods. The 23 
      phthalates were separated on Poroshell 120 EC-C18 column and followed by positive 
      electrospray ionization as well as multi-reaction monitoring provided by a 
      triple-quadrupole tandem mass spectrometer. To reduce contamination, the plastic 
      materials were avoided in sample handling and preparation . The LODs were between 
      0.8 and 15 mug kg(-1) and LOQs were between 10 and 100 mug kg(-1). By using 
      different concentrations: 100, 500, and 1000 mug kg(-1)) for DINP and DIDP; 50, 
      100, and 1000 mug kg(-1) for other 21 phthalate compounds, the spiked recoveries 
      were within 75.5-115.2% and the relative standard deviations (RSDs) were in the 
      range of 3.2-18.9%. The proposed protocol was then applied to the analysis of 623 
      real samples collected from the two sides of the Taiwan Straits, and the DEHP was 
      found in almost all samples tested in this study, with levels ranging from 0.02 
      to 2685 mg kg(-1). The present study demonstrated a rapid, sensitive, and 
      accurate method for determining 23 phthalates in foodstuffs.
CI  - Copyright (c) 2013 Elsevier B.V. All rights reserved.
FAU - Xu, Dunming
AU  - Xu D
AD  - Inspection and Quarantine Technology Center, Xiamen Entry-Exit Inspection and 
      Quarantine Bureau, Xiamen 361026, China. Electronic address: xudm@xmciq.gov.cn.
FAU - Deng, Xiaojun
AU  - Deng X
AD  - Animal Plants & Foods Inspection and Quarantine Technical Center, Shanghai 
      Entry-Exit Inspection and Quarantine Bureau, Shanghai 200135, China.
FAU - Fang, Enhua
AU  - Fang E
AD  - Inspection and Quarantine Technology Center, Xiamen Entry-Exit Inspection and 
      Quarantine Bureau, Xiamen 361026, China.
FAU - Zheng, Xianghua
AU  - Zheng X
AD  - Inspection and Quarantine Technology Center, Xiamen Entry-Exit Inspection and 
      Quarantine Bureau, Xiamen 361026, China.
FAU - Zhou, Yu
AU  - Zhou Y
AD  - Inspection and Quarantine Technology Center, Xiamen Entry-Exit Inspection and 
      Quarantine Bureau, Xiamen 361026, China.
FAU - Lin, Liyi
AU  - Lin L
AD  - Inspection and Quarantine Technology Center, Xiamen Entry-Exit Inspection and 
      Quarantine Bureau, Xiamen 361026, China.
FAU - Chen, Luping
AU  - Chen L
AD  - Inspection and Quarantine Technology Center, Xiamen Entry-Exit Inspection and 
      Quarantine Bureau, Xiamen 361026, China.
FAU - Wu, Ming
AU  - Wu M
AD  - Inspection and Quarantine Technology Center, Xiamen Entry-Exit Inspection and 
      Quarantine Bureau, Xiamen 361026, China.
FAU - Huang, Zhiqiang
AU  - Huang Z
AD  - Hunan Academy of Inspection and Quarantine, Changsha 410007, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20131120
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Phthalic Acids)
RN  - 6O7F7IX66E (phthalic acid)
SB  - IM
MH  - Animals
MH  - Calibration
MH  - Chromatography, Liquid/instrumentation/*methods
MH  - Food Contamination/*analysis
MH  - Limit of Detection
MH  - Phthalic Acids/*analysis
MH  - Tandem Mass Spectrometry/instrumentation/*methods
OTO - NOTNLM
OT  - Foodstuff
OT  - Liquid chromatography tandem mass spectrometry (LC-MS/MS
OT  - Phthalic acid esters (PAEs)
OT  - QuEChERS
OT  - SPE
EDAT- 2013/12/12 06:00
MHDA- 2014/08/26 06:00
CRDT- 2013/12/12 06:00
PHST- 2013/06/19 00:00 [received]
PHST- 2013/11/11 00:00 [revised]
PHST- 2013/11/11 00:00 [accepted]
PHST- 2013/12/12 06:00 [entrez]
PHST- 2013/12/12 06:00 [pubmed]
PHST- 2014/08/26 06:00 [medline]
AID - S0021-9673(13)01788-3 [pii]
AID - 10.1016/j.chroma.2013.11.017 [doi]
PST - ppublish
SO  - J Chromatogr A. 2014 Jan 10;1324:49-56. doi: 10.1016/j.chroma.2013.11.017. Epub 
      2013 Nov 20.