PMID- 24329101
OWN - NLM
STAT- MEDLINE
DCOM- 20141103
LR  - 20140314
IS  - 1502-7686 (Electronic)
IS  - 0036-5513 (Linking)
VI  - 74
IP  - 2
DP  - 2014 Mar
TI  - Diurnal variation of arterial stiffness in healthy individuals of different ages 
      and patients with heart disease.
PG  - 155-62
LID - 10.3109/00365513.2013.864787 [doi]
AB  - BACKGROUND: Arterial stiffness can be measured using various non-invasive 
      methods. It is not well established whether it is necessary to standardize the 
      time of the day when performing these measurements. The aim of the present study 
      is to examine the effect of daytime on arterial stiffness in individuals with and 
      without heart disease. METHODS: We investigated the diurnal variation of 
      cardio-ankle vascular index (CAVI) and carotid femoral pulse wave velocity 
      (cfPWV). CAVI and cfPWV were measured in 70 participants (23 healthy young 
      individuals [HY], 22 healthy elderly individuals [HE], 25 patients with heart 
      disease [HD]) at 09:00, 13:00 and 17:00 h. RESULTS: There was a significant 
      diurnal variation in CAVI with the highest values at 09:00 h in both univariate 
      and multivariate analysis. After adjusting for age, sex and MAP (mean arterial 
      pressure), CAVI maintained a significant highest values at 09:00 h, which was 4% 
      higher than at 13:00 h (p = 0.022) and 5% higher than at 17:00 h (p = 0.002). 
      However, a lack of diurnal variation was found in cfPWV in multivariate analysis 
      in our study population. CONCLUSION: Our findings suggest that it does not appear 
      mandatory to measure cfPWV at the same time of day. However, standardizing the 
      time of day for CAVI is important in routine clinical practice and longitudinal 
      studies.
FAU - Li, Yanlei
AU  - Li Y
AD  - Division Sports Medicine, Institute of Exercise and Health Sciences, University 
      of Basel , Switzerland.
FAU - Cordes, Mareike
AU  - Cordes M
FAU - Recio-Rodriguez, Jose I
AU  - Recio-Rodriguez JI
FAU - Garcia-Ortiz, Luis
AU  - Garcia-Ortiz L
FAU - Hanssen, Henner
AU  - Hanssen H
FAU - Schmidt-Trucksass, Arno
AU  - Schmidt-Trucksass A
LA  - eng
PT  - Journal Article
DEP - 20131212
PL  - England
TA  - Scand J Clin Lab Invest
JT  - Scandinavian journal of clinical and laboratory investigation
JID - 0404375
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Ankle Brachial Index
MH  - Blood Flow Velocity
MH  - Blood Pressure
MH  - Circadian Rhythm/*physiology
MH  - Female
MH  - Heart/*physiology/physiopathology
MH  - Heart Diseases/*physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Sex Factors
MH  - Time Factors
MH  - *Vascular Stiffness
EDAT- 2013/12/18 06:00
MHDA- 2014/11/05 06:00
CRDT- 2013/12/17 06:00
PHST- 2013/12/17 06:00 [entrez]
PHST- 2013/12/18 06:00 [pubmed]
PHST- 2014/11/05 06:00 [medline]
AID - 10.3109/00365513.2013.864787 [doi]
PST - ppublish
SO  - Scand J Clin Lab Invest. 2014 Mar;74(2):155-62. doi: 
      10.3109/00365513.2013.864787. Epub 2013 Dec 12.