PMID- 24329681
OWN - NLM
STAT- MEDLINE
DCOM- 20150602
LR  - 20240109
IS  - 1744-5078 (Electronic)
IS  - 0927-3948 (Linking)
VI  - 22
IP  - 5
DP  - 2014 Oct
TI  - Fundus autofluorescence imaging in multifocal choroiditis: beyond the spots.
PG  - 349-55
LID - 10.3109/09273948.2013.855797 [doi]
AB  - PURPOSE: To describe fundus autofluorescence (FAF) imaging and its correlation to 
      spectral-domain optical coherence tomography (SD-OCT) in retinal areas that 
      appear clinically noninvolved in patients with multifocal choroiditis/punctate 
      inner choroidopathy (MFC/PIC). METHODS: Six patients with MFC or PIC were 
      evaluated during the disease course with multimodal imaging, which included 
      fluorescein angiography, FAF imaging, indocyanine green angiography, and SD-OCT. 
      RESULTS: Five patients had acute and/or scarred chorioretinal spots at 
      presentation. Five patients had choroidal neovascularization. FAF imaging in all 
      patients disclosed diffuse peripapillary and/or posterior-pole 
      hyperautofluorescent plaques in areas that appeared clinically to be noninvolved. 
      Corresponding SD-OCT scans revealed severe disruption of the inner segment/outer 
      segment junction. Findings resolved with corticosteroid treatment Conclusions: 
      FAF imaging of patients with MFC/PIC reveals extensive pathology beyond the 
      clinically apparent spots. FAF findings highlight the areas of corresponding 
      anatomic disruption of the photoreceptor-retinal pigment epithelium complex.
FAU - Kramer, Michal
AU  - Kramer M
AD  - Department of Ophthalmology, Rabin Medical Center , Petach Tikva , Israel .
FAU - Priel, Ethan
AU  - Priel E
LA  - eng
PT  - Journal Article
DEP - 20131211
PL  - England
TA  - Ocul Immunol Inflamm
JT  - Ocular immunology and inflammation
JID - 9312169
RN  - 0 (Coloring Agents)
RN  - 0 (Glucocorticoids)
RN  - IX6J1063HV (Indocyanine Green)
SB  - IM
MH  - Adult
MH  - Choroiditis/*diagnosis/drug therapy
MH  - Coloring Agents
MH  - Female
MH  - Fluorescein Angiography/*methods
MH  - Follow-Up Studies
MH  - Fundus Oculi
MH  - Glucocorticoids/therapeutic use
MH  - Humans
MH  - *Indocyanine Green
MH  - Male
MH  - Multifocal Choroiditis
MH  - Prognosis
MH  - Retinal Pigment Epithelium/*pathology
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence/*methods
MH  - Young Adult
OTO - NOTNLM
OT  - Fundus autofluorescence (FAF)
OT  - multifocal choroiditis (MFC)
OT  - punctate inner choroidopathy (PIC)
OT  - spectral-domain-OCT (SD-OCT)
EDAT- 2013/12/18 06:00
MHDA- 2015/06/03 06:00
CRDT- 2013/12/17 06:00
PHST- 2013/12/17 06:00 [entrez]
PHST- 2013/12/18 06:00 [pubmed]
PHST- 2015/06/03 06:00 [medline]
AID - 10.3109/09273948.2013.855797 [doi]
PST - ppublish
SO  - Ocul Immunol Inflamm. 2014 Oct;22(5):349-55. doi: 10.3109/09273948.2013.855797. 
      Epub 2013 Dec 11.