PMID- 24332354 OWN - NLM STAT- MEDLINE DCOM- 20141001 LR - 20140120 IS - 1872-7727 (Electronic) IS - 0720-048X (Linking) VI - 83 IP - 2 DP - 2014 Feb TI - CMR assessment after a transapical-transcatheter aortic valve implantation. PG - 303-8 LID - S0720-048X(13)00597-4 [pii] LID - 10.1016/j.ejrad.2013.11.007 [doi] AB - AIMS: To describe the time course of myocardial scarring after transapical-transcatheter aortic valve implantation (TA-TAVI) with the Edwards SAPIEN XT and the Edwards SAPIEN prosthesis in a 3-month follow-up study using cardiac magnetic resonance imaging (CMR). METHODS: In 20 TA-TAVI patients, CMR was performed at discharge and 3 months (3M). Cine-MRI was used for left ventricular (LV) functional assessment, and late gadolinium enhancement (LGE) imaging was employed for detecting the presence of myocardial scarring. Special attention was given to any artifacts caused by the prosthesis, which were consequently defined using a three-grade artifact scale. RESULTS: We systematically reported the presence of small LGE hyperintensity relating to the apical segment, with no variation found between discharge and 3M (2.8+/-1.6g vs. 2.35+/-1.1g). LV ejection fraction, end-diastolic, and end-systolic volumes did not significantly vary. A small area of apical akinesia was observed, with no improvement at follow-up. Whereas the Edwards SAPIEN XT prosthesis and the Edwards SAPIEN prosthesis are both constituted by metallic stenting structure, the Edwards SAPIEN was responsible for a larger signal void, thus potentially limiting the diagnostic performance of CMR. CONCLUSIONS: CMR may be performed safely in the context of TA-TAVI. The presence of a very small apical infarction correlating with focal akinesia was observed. As expected, the Edwards SAPIEN XT prosthesis was shown to be particularly suitable for CMR assessment. CI - Copyright (c) 2013 Elsevier Ireland Ltd. All rights reserved. FAU - Biere, Loic AU - Biere L AD - L'UNAM Universite, Angers, France; Universite d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France. Electronic address: lobiere@chu-angers.fr. FAU - Pinaud, Frederic AU - Pinaud F AD - L'UNAM Universite, Angers, France; Universite d'Angers, CHU d'Angers, Service de Chirurgie Cardio-vasculaire et Thoracique, Angers, France; UMR-CNRS 6214, INSERM 1083, faculte de medecine, Angers, France. FAU - Delepine, Stephane AU - Delepine S AD - L'UNAM Universite, Angers, France; Universite d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France. FAU - Grall, Sylvain AU - Grall S AD - L'UNAM Universite, Angers, France; Universite d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France. FAU - Viot, Nathalie AU - Viot N AD - L'UNAM Universite, Angers, France; Universite d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France. FAU - Mateus, Victor AU - Mateus V AD - L'UNAM Universite, Angers, France; Universite d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France. FAU - Rouleau, Frederic AU - Rouleau F AD - L'UNAM Universite, Angers, France; Universite d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France. FAU - Corbeau, Jean-Jacques AU - Corbeau JJ AD - Universite d'Angers, CHU d'Angers, Departement d'anesthesie-reanimation, Angers, France. FAU - Prunier, Fabrice AU - Prunier F AD - L'UNAM Universite, Angers, France; Universite d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France. FAU - De Brux, Jean-Louis AU - De Brux JL AD - L'UNAM Universite, Angers, France; Universite d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France; Universite d'Angers, CHU d'Angers, Service de Chirurgie Cardio-vasculaire et Thoracique, Angers, France. FAU - Willoteaux, Serge AU - Willoteaux S AD - L'UNAM Universite, Angers, France; Universite d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France; Universite d'Angers, CHU d'Angers, Service de Radiologie, Angers, France. FAU - Furber, Alain AU - Furber A AD - L'UNAM Universite, Angers, France; Universite d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France. LA - eng PT - Controlled Clinical Trial PT - Journal Article DEP - 20131123 PL - Ireland TA - Eur J Radiol JT - European journal of radiology JID - 8106411 SB - IM MH - Aged, 80 and over MH - Aortic Valve Stenosis/pathology/surgery MH - *Artifacts MH - Cicatrix/*etiology/*pathology MH - Female MH - Heart Valve Prosthesis Implantation/*adverse effects MH - Humans MH - Magnetic Resonance Imaging, Cine/*methods MH - Male MH - Myocardial Infarction/*etiology/*pathology MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Treatment Outcome OTO - NOTNLM OT - CMR OT - Cardiac magnetic resonance imaging OT - LGE OT - LV OT - Late gadolinium enhancement OT - Myocardial scar OT - TA OT - TAVI OT - TF OT - Trans-apical TAVI OT - cardiac magnetic resonance imaging OT - late gadolinium enhancement OT - left ventricle OT - transapical OT - transcatheter aortic valve implantation OT - transfemoral EDAT- 2013/12/18 06:00 MHDA- 2014/10/02 06:00 CRDT- 2013/12/17 06:00 PHST- 2013/07/31 00:00 [received] PHST- 2013/10/10 00:00 [revised] PHST- 2013/11/02 00:00 [accepted] PHST- 2013/12/17 06:00 [entrez] PHST- 2013/12/18 06:00 [pubmed] PHST- 2014/10/02 06:00 [medline] AID - S0720-048X(13)00597-4 [pii] AID - 10.1016/j.ejrad.2013.11.007 [doi] PST - ppublish SO - Eur J Radiol. 2014 Feb;83(2):303-8. doi: 10.1016/j.ejrad.2013.11.007. Epub 2013 Nov 23.