PMID- 24332810
OWN - NLM
STAT- MEDLINE
DCOM- 20140929
LR  - 20200810
IS  - 2212-4632 (Electronic)
IS  - 1883-1958 (Linking)
VI  - 58
IP  - 1
DP  - 2014 Jan
TI  - Differences of salivary cortisol levels between long-term and short-term wearers 
      of dento-maxillary prosthesis due to head and neck cancer resection.
PG  - 41-7
LID - S1883-1958(13)00124-2 [pii]
LID - 10.1016/j.jpor.2013.10.001 [doi]
AB  - PURPOSE: The purpose of this study was to use cortisol awakening response (CAR) 
      to investigate the differences in daily life stress experienced by individuals 
      wearing either a long-term (LT) or a short-term (ST) dento-maxillary prosthesis 
      following head and neck cancer (HNC) resection. Also we used the University of 
      Washington Quality of Life (UW-QOL) version 4 questionnaire to evaluate the 
      differences in quality of life (QOL) scores between ST and LT wearers of a 
      dento-maxillary prosthesis. METHODS: Salivary samples were collected from 11 LT 
      and 10 ST prosthesis wearers on two consecutive days at two time points, 
      immediately after waking up (T0) and 30min later (T30), by passive drool 
      collection. Cortisol levels were measured using a high sensitivity salivary 
      cortisol enzyme immunoassay kit (Salimetrics, LLC, State College, PA, USA) and 
      CAR (the differences between the cortisol levels at T0 and T30) was compared 
      between LT and ST prosthesis wearers. In addition, both the groups completed the 
      UW-QOL questionnaire and the scores were compared. RESULTS: A significant 
      difference was observed in CAR between the two groups. CAR of the ST prosthesis 
      wearers was significantly lower compared with that of the LT prosthesis wearers; 
      moreover, the ST prosthesis wearers revealed significantly lower total UW-QOL 
      scores and there were significant differences in appearance, activity, 
      recreation, speech, and anxiety. CONCLUSION: Within the limitations of this 
      study, the findings suggest that individuals wearing ST dento-maxillary 
      prostheses following HNC resection experience some sort of daily life stress and 
      complicated socio-demographic factors may influence their QOL.
CI  - Copyright (c) 2013 Japan Prosthodontic Society. Published by Elsevier Ltd. All 
      rights reserved.
FAU - Kosaka, Moe
AU  - Kosaka M
AD  - Department of Maxillofacial Prosthetics, Graduate School of Medical and Dental 
      Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 
      113-8549, Japan. Electronic address: kosamfp@tmd.ac.jp.
FAU - Sumita, Yuka I
AU  - Sumita YI
AD  - Department of Maxillofacial Prosthetics, Graduate School of Medical and Dental 
      Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 
      113-8549, Japan.
FAU - Otomaru, Takafumi
AU  - Otomaru T
AD  - Department of Maxillofacial Prosthetics, Graduate School of Medical and Dental 
      Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 
      113-8549, Japan.
FAU - Taniguchi, Hisashi
AU  - Taniguchi H
AD  - Department of Maxillofacial Prosthetics, Graduate School of Medical and Dental 
      Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 
      113-8549, Japan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20131214
PL  - Japan
TA  - J Prosthodont Res
JT  - Journal of prosthodontic research
JID - 101490359
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Demography
MH  - Female
MH  - Head and Neck Neoplasms/*physiopathology/surgery
MH  - Humans
MH  - Hydrocortisone/*analysis
MH  - Male
MH  - Maxillofacial Prosthesis/*adverse effects/*psychology
MH  - Middle Aged
MH  - Quality of Life
MH  - Saliva/*chemistry
MH  - Stress, Psychological/*etiology/*physiopathology
MH  - Surveys and Questionnaires
MH  - Time Factors
OTO - NOTNLM
OT  - Cortisol levels
OT  - Dento-maxillary prosthesis wearers
OT  - Saliva
EDAT- 2013/12/18 06:00
MHDA- 2014/09/30 06:00
CRDT- 2013/12/17 06:00
PHST- 2012/11/14 00:00 [received]
PHST- 2013/10/02 00:00 [revised]
PHST- 2013/10/15 00:00 [accepted]
PHST- 2013/12/17 06:00 [entrez]
PHST- 2013/12/18 06:00 [pubmed]
PHST- 2014/09/30 06:00 [medline]
AID - S1883-1958(13)00124-2 [pii]
AID - 10.1016/j.jpor.2013.10.001 [doi]
PST - ppublish
SO  - J Prosthodont Res. 2014 Jan;58(1):41-7. doi: 10.1016/j.jpor.2013.10.001. Epub 
      2013 Dec 14.