PMID- 24333339
OWN - NLM
STAT- MEDLINE
DCOM- 20141124
LR  - 20140303
IS  - 1879-0542 (Electronic)
IS  - 0165-2478 (Linking)
VI  - 158
IP  - 1-2
DP  - 2014 Mar-Apr
TI  - Cross-presentation by human dendritic cell subsets.
PG  - 73-8
LID - S0165-2478(13)00206-X [pii]
LID - 10.1016/j.imlet.2013.12.001 [doi]
AB  - Dendritic cells (DCs) are a heterogeneous population of professional 
      antigen-presenting cells. Several murine DC subsets differ in their phenotype and 
      functional properties, in particular in their ability to cross-present antigens 
      (i.e. to present exogenous antigens on their MHC class I molecules). In humans, 
      distinct DC subpopulations have also been identified but whether some human DC 
      subsets are also specialized at cross-presentation remains debated. Here we 
      review the DC subsets that have been identified in humans and we discuss recent 
      work that addresses their ability to cross-present antigens and their efficiency 
      for CD8(+) T cells activation.
CI  - Copyright (c) 2013 Elsevier B.V. All rights reserved.
FAU - Segura, Elodie
AU  - Segura E
AD  - INSERM U932, 26 rue d'Ulm, 75005 Paris, France; Institut Curie, Section 
      Recherche, 26 rue d'Ulm, 75005 Paris, France. Electronic address: 
      elodie.segura@curie.fr.
FAU - Amigorena, Sebastian
AU  - Amigorena S
AD  - INSERM U932, 26 rue d'Ulm, 75005 Paris, France; Institut Curie, Section 
      Recherche, 26 rue d'Ulm, 75005 Paris, France.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20131212
PL  - Netherlands
TA  - Immunol Lett
JT  - Immunology letters
JID - 7910006
RN  - 0 (Antigens)
SB  - IM
MH  - Animals
MH  - Antigens/immunology/metabolism
MH  - Biological Evolution
MH  - Cell Differentiation
MH  - Cell Lineage
MH  - *Cross-Priming
MH  - Dendritic Cells/*immunology
MH  - Gene Expression Profiling
MH  - Humans
MH  - Mice
OTO - NOTNLM
OT  - CD8+ T cells
OT  - Cross-presentation
OT  - Dendritic cells
OT  - Vaccination
EDAT- 2013/12/18 06:00
MHDA- 2014/12/15 06:00
CRDT- 2013/12/17 06:00
PHST- 2013/09/02 00:00 [received]
PHST- 2013/11/22 00:00 [revised]
PHST- 2013/12/01 00:00 [accepted]
PHST- 2013/12/17 06:00 [entrez]
PHST- 2013/12/18 06:00 [pubmed]
PHST- 2014/12/15 06:00 [medline]
AID - S0165-2478(13)00206-X [pii]
AID - 10.1016/j.imlet.2013.12.001 [doi]
PST - ppublish
SO  - Immunol Lett. 2014 Mar-Apr;158(1-2):73-8. doi: 10.1016/j.imlet.2013.12.001. Epub 
      2013 Dec 12.