PMID- 24337057 OWN - NLM STAT- MEDLINE DCOM- 20150406 LR - 20191112 IS - 1806-9339 (Electronic) IS - 0100-7203 (Linking) VI - 35 IP - 10 DP - 2013 Oct TI - [Eosinophilia in peripheral blood of women with recurrent vaginal candidiasis]. PG - 453-7 LID - S0100-72032013001000005 [pii] AB - PURPOSE: To quantify the number of defense cells and immunoglobulin E (IgE) levels in peripheral blood sampled from women with recurrent vulvovaginal candidiasis. METHODS: A cross-sectional study was conducted on 60 women, 40 with vulvovaginal candidiasis and 20 controls. The defense cells were identified using an impedance system combined with flow cytometry and total and specific IgE was measured by chemiluminescence. The Mann-Whitney test was used for nominal variables and the Spearman test was used to determine the correlation of IgE concentration and eosinophils in peripheral blood. RESULTS: The number of eosinophils in peripheral blood from patients with recurrent vulvovaginal candidiasis, 302.60 (+/- 253.07), was significantly higher compared to control, 175.75 (+/- 109.24) (p=0.037). Serum levels of total and specific IgE were similar in the groups of women with and without recurrent vulvovaginal candidiasis (p=0.361). However, there was a moderate positive correlation between eosinophils and total serum IgE in the candidiasis group (r=0.25). CONCLUSION: Women with recurrent vulvovaginal candidiasis are more likely to have eosinophils in peripheral blood. FAU - Queiroz Filho, Jose AU - Queiroz Filho J FAU - Goncalves, Ana Katherine AU - Goncalves AK FAU - Cavalcante, Geraldo Barroso Jr AU - Cavalcante GB Jr FAU - Pessoa, Daliana Caldas AU - Pessoa DC FAU - Eleuterio, Jose Jr AU - Eleuterio J Jr FAU - Giraldo, Paulo Cesar AU - Giraldo PC FAU - Sales, Valeria Soraya de Farias AU - Sales VS LA - por PT - English Abstract PT - Journal Article TT - Eosinofilia no sangue periferico de mulheres com candidiase vaginal recorrente. PL - Brazil TA - Rev Bras Ginecol Obstet JT - Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia JID - 9214757 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Candidiasis, Vulvovaginal/*blood/complications MH - Cross-Sectional Studies MH - Eosinophilia/*blood/*microbiology MH - Female MH - Humans MH - Immunoglobulin E/blood MH - Recurrence EDAT- 2013/12/18 06:00 MHDA- 2015/04/07 06:00 CRDT- 2013/12/17 06:00 PHST- 2013/07/10 00:00 [received] PHST- 2013/10/04 00:00 [accepted] PHST- 2013/12/17 06:00 [entrez] PHST- 2013/12/18 06:00 [pubmed] PHST- 2015/04/07 06:00 [medline] AID - S0100-72032013001000005 [pii] AID - 10.1590/s0100-72032013001000005 [doi] PST - ppublish SO - Rev Bras Ginecol Obstet. 2013 Oct;35(10):453-7. doi: 10.1590/s0100-72032013001000005.