PMID- 24341672
OWN - NLM
STAT- MEDLINE
DCOM- 20140321
LR  - 20220408
IS  - 1471-2458 (Electronic)
IS  - 1471-2458 (Linking)
VI  - 13
DP  - 2013 Dec 17
TI  - Drug-related problems in type 2 diabetes mellitus patients with dyslipidemia.
PG  - 1192
LID - 10.1186/1471-2458-13-1192 [doi]
AB  - BACKGROUND: Drug-Related Problems (DRPs) commonly occur among type 2 diabetes 
      mellitus (T2DM) patients. However, few studies have been performed on T2DM 
      patients with dyslipidemia. This purpose of this study was to assess drug-related 
      problems (DRPs) and factors associated with its occurrence. METHODS: The 
      retrospective study involved 208 T2DM in-patients and out-patients with 
      dyslipidemia, and was conducted at a tertiary hospital in Malaysia from January 
      2009 to December 2011. The identification and assessment of DRPs were based on 
      the Pharmaceutical Care Network Europe (PCNE) tool version 5.01. The potentially 
      inappropriate medication use in older adults was assessed based on the American 
      Geriatrics Society updated Beers Criteria. RESULTS: A total of 406 DRPs were 
      identified. Among these patients, 91.8% had at least one DRP, averaging 1.94+/-1.10 
      problems per patient. The majority of T2DM patients with dyslipidemia (91.8%) had 
      at least one DRP. The most frequent types of DRP were potential drug-drug 
      interaction (18.0%), drug not taken or administered (14.3%) and insufficient 
      awareness of health and diseases (11.8%). Anti-hypertensive, lipid-modifying and 
      anti-diabetic agents were the drug classes that were most likely to be associated 
      with DRPs. Male gender, renal impairment, polypharmacy and poor lipid control 
      were factors that were significantly associated with DRP in diabetic dyslipidemia 
      patients. CONCLUSION: Early identification of DRPs and factors associated with 
      them are essential to prevent and resolve DRPs in T2DM patients with 
      dyslipidemia.
FAU - Zaman Huri, Hasniza
AU  - Zaman Huri H
AD  - Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur 
      50603, Malaysia. hasnizazh@um.edu.my.
FAU - Chai Ling, Lee
AU  - Chai Ling L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20131217
PL  - England
TA  - BMC Public Health
JT  - BMC public health
JID - 100968562
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (Hypolipidemic Agents)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Comorbidity
MH  - Diabetes Mellitus, Type 2/*drug therapy/*epidemiology
MH  - Dyslipidemias/*drug therapy/*epidemiology
MH  - Female
MH  - Humans
MH  - Hypoglycemic Agents/*adverse effects
MH  - Hypolipidemic Agents/*adverse effects
MH  - Malaysia/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Treatment Outcome
MH  - Young Adult
PMC - PMC3890513
EDAT- 2013/12/18 06:00
MHDA- 2014/03/22 06:00
PMCR- 2013/12/17
CRDT- 2013/12/18 06:00
PHST- 2013/08/05 00:00 [received]
PHST- 2013/12/12 00:00 [accepted]
PHST- 2013/12/18 06:00 [entrez]
PHST- 2013/12/18 06:00 [pubmed]
PHST- 2014/03/22 06:00 [medline]
PHST- 2013/12/17 00:00 [pmc-release]
AID - 1471-2458-13-1192 [pii]
AID - 10.1186/1471-2458-13-1192 [doi]
PST - epublish
SO  - BMC Public Health. 2013 Dec 17;13:1192. doi: 10.1186/1471-2458-13-1192.