PMID- 24343976
OWN - NLM
STAT- MEDLINE
DCOM- 20140630
LR  - 20191210
IS  - 1932-863X (Electronic)
IS  - 1932-8621 (Linking)
VI  - 7
IP  - 4
DP  - 2013 Nov
TI  - Large variation of severity and longitudinal change of symptom distress among 
      patients with personality disorders.
PG  - 265-76
LID - 10.1002/pmh.1226 [doi]
AB  - Main objectives were to investigate (1) the longitudinal course of symptom 
      distress among patients with personality disorders (PD) and (2) how different 
      Axis-I and Axis-II pathology and treatment factors predict or moderate long-term 
      outcome. All patients (n = 751) were admitted to short-term day hospital 
      treatment, and 47% continued in group psychotherapy (mean duration 2.3 years). 
      Symptom distress was assessed repeatedly over 5 years (Symptom Check List 90-R). 
      Mixed models were chosen for statistical analyses. A main finding was the large 
      variation in severity and longitudinal course of symptom distress. Five-year 
      trends ranged from full symptom remission (31%) to pervasive, severe distress 
      (36%). Co-occurring Axis-I disorders did not explain longitudinal variability of 
      symptom distress. However, the presence and increasing severity of Axis-II 
      pathology was strongly associated with more severe baseline symptom distress. 
      Poor long-term outcomes were associated with the combination of avoidant PD and 
      long treatment durations (>2.5 years), and borderline PD and short treatment 
      durations (<0.4 years). Contrastingly, considerable symptom relief was associated 
      with borderline PD and long treatment duration. In conclusion, the severity and 
      longitudinal course of symptom distress among PD patients is closely associated 
      with their personality structures and not sufficiently explained by Axis-I 
      comorbidity.
CI  - Copyright (c) 2013 John Wiley & Sons, Ltd.
FAU - Kvarstein, Elfrida H
AU  - Kvarstein EH
AD  - Research Group at the Department for Personality Psychiatry, Oslo University 
      Hospital, Ulleval, Norway.
FAU - Karterud, Sigmund
AU  - Karterud S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130312
PL  - England
TA  - Personal Ment Health
JT  - Personality and mental health
JID - 101473502
RN  - 0 (Antidepressive Agents)
SB  - IM
MH  - Adult
MH  - Antidepressive Agents/therapeutic use
MH  - Anxiety Disorders/epidemiology
MH  - Comorbidity
MH  - *Day Care, Medical
MH  - Diagnostic and Statistical Manual of Mental Disorders
MH  - Disease Progression
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Interview, Psychological
MH  - Linear Models
MH  - Male
MH  - Mood Disorders/epidemiology
MH  - Outcome Assessment, Health Care/*statistics & numerical data
MH  - Patient Compliance
MH  - Personality Disorders/epidemiology/*psychology/therapy
MH  - *Psychotherapy, Group
MH  - Remission Induction
MH  - Self Report
MH  - Severity of Illness Index
MH  - Stress, Psychological/epidemiology/*psychology
MH  - Time Factors
EDAT- 2013/12/18 06:00
MHDA- 2014/07/01 06:00
CRDT- 2013/12/18 06:00
PHST- 2012/06/26 00:00 [received]
PHST- 2012/12/03 00:00 [revised]
PHST- 2013/01/04 00:00 [accepted]
PHST- 2013/12/18 06:00 [entrez]
PHST- 2013/12/18 06:00 [pubmed]
PHST- 2014/07/01 06:00 [medline]
AID - 10.1002/pmh.1226 [doi]
PST - ppublish
SO  - Personal Ment Health. 2013 Nov;7(4):265-76. doi: 10.1002/pmh.1226. Epub 2013 Mar 
      12.