PMID- 24348588
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20131218
LR  - 20211021
IS  - 1726-913X (Print)
IS  - 1726-9148 (Electronic)
IS  - 1726-913X (Linking)
VI  - 11
IP  - 3
DP  - 2013 Summer
TI  - Effect of ethnicity, dietary intake and physical activity on plasma adiponectin 
      concentrations among malaysian patients with type 2 diabetes mellitus.
PG  - 167-74
LID - 10.5812/ijem.8298 [doi]
AB  - BACKGROUND: The Malaysian Health and morbidity Survey (2006) reported the highest 
      prevalence of type 2 diabetes mellitus (T2DM) among the Indian population 
      compared to the Malay and Chinese populations. Many studies have supported the 
      important role of adiponectin in insulin-sensitizing, which is associated with 
      T2DM. These studies have raised a research question whether the variation in 
      prevalence is related to the adiponectin concentrations or the lifestyle factors. 
      OBJECTIVES: The purpose of this study is to determine whether the adiponectin 
      concentrations differ between the Malay, Chinese and the Indian populations with 
      T2DM. It is to investigate the association of adiponectin concentrations with 
      ethnicity, dietary intake and physical activity too. MATERIALS AND METHODS: In 
      this cross-sectional study, a total of 210 T2DM patients with mean (SD) age of 
      56.73 (10.23) years were recruited from Penang, Malaysia. Data on demographic 
      background, medical history, anthropometry (weight, height, visceral fat, 
      percentage of body fat and waist circumference), dietary intake (3 days 24 hours 
      diet recall) and physical activity (International Physical Activity 
      Questionnaire) were obtained accordingly. Plasma adiponectin and routine 
      laboratory tests (fasting blood sugar, HbA1c, total cholesterol, LDL, HDL and 
      triglyceride) were performed according to standard procedure. RESULTS: After 
      adjustment for physical activity and dietary intakes, the Indian population had 
      significantly lower adiponectin concentrations (P = 0.003) when compared with the 
      Malay and the Chinese populations, The Indian population also had significantly 
      higher value of HbA1c (P = 0.017) and significantly lower HDL (P = 0.013). Plasma 
      adiponectin concentrations was significantly associated with ethnicity (P = 
      0.011), dietary carbohydrate (P = 0.003) and physical activity total MET score (P 
      = 0.026), after medical history, age, sex, total cholesterol and visceral fat 
      adjusted. However, dietary carbohydrate and physical activity did not show 
      significantly difference among the various ethnic groups. CONCLUSIONS: In 
      conclusion, lower concentration of adiponectin in the Indian population when 
      compared with the Malay and the Chinese populations is not associated with 
      lifestyle factors. The possibility of adiponectin gene polymorphism should be 
      discussed further.
FAU - Chin, Koo Hui
AU  - Chin KH
AD  - Nutrition Program, School of Health Sciences, Universiti Sains Malaysia, 
      Malaysia, Malaysia.
FAU - Sathyasurya, Daniel Robert
AU  - Sathyasurya DR
AD  - Nutrition Program, School of Health Sciences, Universiti Sains Malaysia, 
      Malaysia, Malaysia.
FAU - Abu Saad, Hazizi
AU  - Abu Saad H
AD  - Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, 
      Universiti Putra Malaysia, Malaysia.
FAU - Jan Mohamed, Hamid Jan B
AU  - Jan Mohamed HJ
AD  - Nutrition Program, School of Health Sciences, Universiti Sains Malaysia, 
      Malaysia, Malaysia.
LA  - eng
PT  - Journal Article
DEP - 20130701
PL  - Netherlands
TA  - Int J Endocrinol Metab
JT  - International journal of endocrinology and metabolism
JID - 101235597
PMC - PMC3860115
OTO - NOTNLM
OT  - Adiponectin
OT  - Chinese
OT  - Diabetes Mellitus, Type 2
OT  - Diet Records
OT  - Indian
OT  - Malaysia
OT  - Motor Activity
EDAT- 2013/12/19 06:00
MHDA- 2013/12/19 06:01
PMCR- 2013/06/01
CRDT- 2013/12/19 06:00
PHST- 2012/11/03 00:00 [received]
PHST- 2013/02/21 00:00 [revised]
PHST- 2013/03/04 00:00 [accepted]
PHST- 2013/12/19 06:00 [entrez]
PHST- 2013/12/19 06:00 [pubmed]
PHST- 2013/12/19 06:01 [medline]
PHST- 2013/06/01 00:00 [pmc-release]
AID - 10.5812/ijem.8298 [doi]
PST - ppublish
SO  - Int J Endocrinol Metab. 2013 Summer;11(3):167-74. doi: 10.5812/ijem.8298. Epub 
      2013 Jul 1.