PMID- 24349667
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20131218
LR  - 20211021
IS  - 2008-2010 (Print)
IS  - 2008-322X (Electronic)
IS  - 2008-322X (Linking)
VI  - 8
IP  - 3
DP  - 2013 Jul
TI  - Rate of Post-traumatic Endophthalmitis with or without Injection of Balanced Salt 
      Solution.
PG  - 237-43
AB  - PURPOSE: In a study complementing a previous multicenter randomized clinical 
      trial on prophylactic injection of intraocular antibiotics during primary repair 
      of penetrating eye injuries (PEIs), we sought to determine whether needle 
      entrance and injection of balanced salt solution (BSS), per se, could increase 
      the rate of acute post-traumatic bacterial endophthalmitis (APBE). METHODS: 
      Patients randomized to the BSS injection arm (n=167) of the Traumatic 
      Endophthalmitis Trial, and eligible patients who had refused enrollment and 
      received no intraocular injections during primary repair (n=111) were compared 
      for the development of APBE. RESULTS: APBE occurred in 8 of 167 (4.8%) eyes in 
      the BSS group and in 5 of 111 (4.5%) eyes in the non-injection group (P=0.91). 
      Retained intraocular foreign bodies were present in 46 eyes including 25 (15%) 
      eyes in the BSS injection group and 21 (18.9%) eyes in the non-injection group 
      (P=0.38). Logistic regression analysis showed no significant difference between 
      BSS injected and non-injected eyes in terms of APBE (P=0.69). However, the 
      presence of intraocular foreign bodies was strongly associated with the risk of 
      endophthalmitis (P<0.001, OR=14.1, 95% CI: 4.1-48.5). CONCLUSION: Needle entrance 
      and intraocular injection of BSS during primary repair of PEIs does not increase 
      the risk of APBE.
FAU - Rafati, Nasrin
AU  - Rafati N
AD  - Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, 
      Tehran, Iran.
FAU - Azarmina, Mohsen
AU  - Azarmina M
AD  - Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, 
      Tehran, Iran.
FAU - Zaeri, Farid
AU  - Zaeri F
AD  - Department of Biostatistics, Faculty of Paramedical Sciences, Shahid Beheshti 
      University of Medical Sciences, Tehran, Iran.
FAU - Yazdani, Shahin
AU  - Yazdani S
AD  - Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, 
      Tehran, Iran.
FAU - Soheilian, Roham
AU  - Soheilian R
AD  - Medical Student, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
FAU - Soheilian, Masoud
AU  - Soheilian M
AD  - Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, 
      Tehran, Iran.
LA  - eng
PT  - Journal Article
PL  - United Arab Emirates
TA  - J Ophthalmic Vis Res
JT  - Journal of ophthalmic & vision research
JID - 101497643
PMC - PMC3853788
OTO - NOTNLM
OT  - Bacterial Endophthalmitis
OT  - Intraocular Injection
OT  - Penetrating Eye Injury
EDAT- 2013/12/19 06:00
MHDA- 2013/12/19 06:01
PMCR- 2013/07/01
CRDT- 2013/12/19 06:00
PHST- 2012/08/16 00:00 [received]
PHST- 2012/12/05 00:00 [accepted]
PHST- 2013/12/19 06:00 [entrez]
PHST- 2013/12/19 06:00 [pubmed]
PHST- 2013/12/19 06:01 [medline]
PHST- 2013/07/01 00:00 [pmc-release]
AID - JOVR-08-237 [pii]
PST - ppublish
SO  - J Ophthalmic Vis Res. 2013 Jul;8(3):237-43.