PMID- 24352125 OWN - NLM STAT- MEDLINE DCOM- 20160906 LR - 20171116 IS - 1758-1052 (Electronic) IS - 0956-4624 (Linking) VI - 25 IP - 7 DP - 2014 Jun TI - A case of multicentric Castleman's disease in HIV infection with the rare complication of acquired angioedema. PG - 523-5 LID - 10.1177/0956462413516941 [doi] AB - Multicentric Castleman's disease (MCD), a polyclonal lymphoproliferative disorder of unknown aetiology, is a well-recognised complication of HIV disease. We present a case of MCD in an HIV-positive patient that is unusual on two counts: our patient's MCD first presented in the context of an immune restoration inflammatory syndrome (IRIS), following the initiation of highly active antiretroviral therapy (HAART). In addition, her MCD was associated with the unusual complication of acquired angioedema (AAE), which resolved following treatment of the MCD. While AAE is frequently found to have an underlying diagnosis of a lymphoproliferative disease, this is the first reported case linking AAE to MCD. CI - (c) The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav. FAU - Fernando, I AU - Fernando I AD - Chalmers Sexual Health Centre, NHS Lothian, Edinburgh, UK imali.fernando@live.co.uk. FAU - Scott, G AU - Scott G AD - Chalmers Sexual Health Centre, NHS Lothian, Edinburgh, UK. LA - eng PT - Case Reports PT - Journal Article DEP - 20131218 PL - England TA - Int J STD AIDS JT - International journal of STD & AIDS JID - 9007917 RN - 0 (Antineoplastic Agents) RN - 4F4X42SYQ6 (Rituximab) RN - Acquired angioedema RN - Multi-centric Castleman's Disease SB - IM MH - Adult MH - Angioedema/*complications MH - Antineoplastic Agents/*therapeutic use MH - Antiretroviral Therapy, Highly Active/adverse effects MH - Castleman Disease/*diagnosis/*drug therapy MH - Female MH - HIV Infections/complications/drug therapy/*immunology MH - HIV Seropositivity/complications MH - HIV-1 MH - Herpesvirus 8, Human/*isolation & purification MH - Humans MH - Rituximab/*therapeutic use MH - Treatment Outcome OTO - NOTNLM OT - AIDS OT - HAART (highly-active anti-retroviral therapy) OT - HHV-8 OT - HIV OT - Multicentric Castleman's disease OT - acquired angioedema OT - human herpes virus-8 OT - immune restoration inflammatory syndrome EDAT- 2013/12/20 06:00 MHDA- 2016/09/07 06:00 CRDT- 2013/12/20 06:00 PHST- 2013/09/23 00:00 [received] PHST- 2013/11/23 00:00 [accepted] PHST- 2013/12/20 06:00 [entrez] PHST- 2013/12/20 06:00 [pubmed] PHST- 2016/09/07 06:00 [medline] AID - 0956462413516941 [pii] AID - 10.1177/0956462413516941 [doi] PST - ppublish SO - Int J STD AIDS. 2014 Jun;25(7):523-5. doi: 10.1177/0956462413516941. Epub 2013 Dec 18.