PMID- 24352827
OWN - NLM
STAT- MEDLINE
DCOM- 20150109
LR  - 20211021
IS  - 1433-0385 (Electronic)
IS  - 0009-4722 (Linking)
VI  - 85
IP  - 5
DP  - 2014 May
TI  - [Peroral endoscopic myotomy for treatment of achalasia. Literature review and own 
      initial experience].
PG  - 420-32
LID - 10.1007/s00104-013-2639-0 [doi]
AB  - Peroral endoscopic myotomy (POEM) is a new, purely endoscopic procedure for 
      treatment of achalasia. Due to the lack of incisions POEM can be regarded as a 
      true NOTES procedure. With POEM a myotomy is created in a similar fashion to the 
      previous standard treatment, laparoscopic Heller myotomy (LHM). The relatively 
      free choice of length and localization of the myotomy may be regarded as 
      advantages of POEM. The procedure starts with a mucosal incision (mucosal entry) 
      followed by preparation of a submucosal tunnel crossing the esophagogastric 
      junction and creation of a myotomy in an antegrade direction before the mucosal 
      access is closed with endoscopic clip placement. Since the first description of 
      the application of POEM in humans in 2010 by the pioneer Haruhiro Inoue, 
      Yokohama, Japan, it has been used increasingly and investigated in some centers 
      in Asia, the U.S.A. and also Europe. The results are very promising. Although the 
      procedure is technically demanding it can be performed safely with low 
      complication rates. The POEM procedure achieves very good control of dysphagia 
      and gastroesophageal reflux witch is only a rare side-effect witch is 
      well-controllable with proton pump inhibitors (PPI). We review the currently 
      available data from the literature and present our own initial series of  14 
      patients treated with POEM.
FAU - von Rahden, B H A
AU  - von Rahden BH
AD  - Klinik fur Allgemein-, Visceral-, Gefass- und Kinderchirurgie, Zentrum fur 
      operative Medizin (ZOM), Universitatsklinikum Wurzburg, Oberdurrbacherstr. 6, 
      97080, Wurzburg, Deutschland, Rahden_B@chirurgie.uni-wuerzburg.de.
FAU - Filser, J
AU  - Filser J
FAU - Reimer, S
AU  - Reimer S
FAU - Inoue, H
AU  - Inoue H
FAU - Germer, C-T
AU  - Germer CT
LA  - ger
PT  - English Abstract
PT  - Journal Article
TT  - Perorale endoskopische Myotomie zur Therapie der Achalasie. Literaturuberblick 
      und eigene initiale Erfahrung.
PL  - Germany
TA  - Chirurg
JT  - Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
JID - 16140410R
SB  - IM
MH  - Adult
MH  - Aged
MH  - Esophageal Achalasia/classification/diagnosis/*surgery
MH  - Esophagoplasty/*methods
MH  - *Esophagoscopy
MH  - Female
MH  - Humans
MH  - Male
MH  - Manometry
MH  - Middle Aged
MH  - Natural Orifice Endoscopic Surgery/*methods
MH  - Postoperative Complications/etiology
MH  - Signal Processing, Computer-Assisted
EDAT- 2013/12/20 06:00
MHDA- 2015/01/13 06:00
CRDT- 2013/12/20 06:00
PHST- 2013/12/20 06:00 [entrez]
PHST- 2013/12/20 06:00 [pubmed]
PHST- 2015/01/13 06:00 [medline]
AID - 10.1007/s00104-013-2639-0 [doi]
PST - ppublish
SO  - Chirurg. 2014 May;85(5):420-32. doi: 10.1007/s00104-013-2639-0.