PMID- 24357808
OWN - NLM
STAT- MEDLINE
DCOM- 20140507
LR  - 20151119
IS  - 1462-0332 (Electronic)
IS  - 1462-0324 (Linking)
VI  - 53
IP  - 4
DP  - 2014 Apr
TI  - The Gout Assessment Questionnaire 2.0: cross-cultural translation into Dutch, 
      aspects of validity and linking to the International Classification of 
      Functioning, Disability and Health.
PG  - 678-85
LID - 10.1093/rheumatology/ket423 [doi]
AB  - OBJECTIVES: The Gout Assessment Questionnaire 2.0 (GAQ2.0) is a disease-specific 
      patient-reported outcome measure for gout that distinguishes five different 
      subscales and comprises overall 31 questions. The aims of this study were to 
      translate the GAQ2.0 into Dutch and to test clinimetric properties. METHODS: 
      Recommendations for translation and cross-cultural adaptation were followed and 
      no cultural adaptations were needed. The resulting Dutch GAQ2.0 was administered 
      to patients registered at the rheumatology outpatient clinic diagnosed with gout. 
      Internal consistency was tested using Cronbach's alpha, reliability using intraclass 
      correlation coefficient (ICC), content validity by linkage to the International 
      Classification of Functioning, Disability and Health (ICF) and construct validity 
      by correlating the subscales of the GAQ2.0 with the HAQ disability index (HAQ-DI) 
      and 36-item Short Form Health Survey (SF-36). RESULTS: A total of 126 patients 
      [106 (84%) male, mean age 66.6 years (s.d. 10.4), mean disease duration 11.2 
      years (s.d. 10.6)] completed a number of questionnaires, including the GAQ2.0, 
      HAQ-DI and SF-36, and underwent a clinical examination. Internal consistency was 
      sufficient (Cronbach's alpha = 0.83-0.94), except for the subscale gout medication 
      side effects (Cronbach's alpha = 0.51). Test-retest reliability was good (ICCs 
      0.73-0.86) for all subscales, but moderate for the subscale unmet gout treatment 
      need (ICC 0.56). Gout impact (GI) subscale scores showed only weak to moderate 
      correlations with HAQ-DI and SF-36, but stronger emphasis on the emotional 
      consequences of gout. Also, it correlated better with gout-specific outcomes such 
      as the number of gout flares and pain. CONCLUSION: The Dutch GAQ2.0 shows 
      sufficient evidence of validity to assess disease-specific functioning and health 
      in patients with gout and seems to capture different aspects than those 
      represented in the HAQ and SF-36.
FAU - Spaetgens, Bart
AU  - Spaetgens B
AD  - Maastricht University Medical Center, PO Box 5800, NL-6202 AZ Maastricht, The 
      Netherlands. bartholomeus.spaetgens@mumc.nl.
FAU - van der Linden, Sjef
AU  - van der Linden S
FAU - Boonen, Annelies
AU  - Boonen A
LA  - eng
PT  - Journal Article
DEP - 20131218
PL  - England
TA  - Rheumatology (Oxford)
JT  - Rheumatology (Oxford, England)
JID - 100883501
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Gout/*diagnosis
MH  - Humans
MH  - International Classification of Functioning, Disability and Health/statistics & 
      numerical data
MH  - Male
MH  - Middle Aged
MH  - *Patient Outcome Assessment
MH  - Quality of Life
MH  - Reproducibility of Results
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
MH  - Translations
OTO - NOTNLM
OT  - Gout Assessment Questionnaire
OT  - gout
OT  - patient reported outcome
OT  - quality of life
OT  - validation
OT  - validity
EDAT- 2013/12/21 06:00
MHDA- 2014/05/08 06:00
CRDT- 2013/12/21 06:00
PHST- 2013/12/21 06:00 [entrez]
PHST- 2013/12/21 06:00 [pubmed]
PHST- 2014/05/08 06:00 [medline]
AID - ket423 [pii]
AID - 10.1093/rheumatology/ket423 [doi]
PST - ppublish
SO  - Rheumatology (Oxford). 2014 Apr;53(4):678-85. doi: 10.1093/rheumatology/ket423. 
      Epub 2013 Dec 18.